Case Report: A Metabolic Complete Response to Upfront Osimertinib in a Smoker Non-Small Cell Lung Cancer Patient Harbouring G719A/V769M Complex Mutation.

Complex mutations are rare in non-small cell lung cancer (NSCLC). Limited clinical evidence is available on the efficacy of tyrosine kinase inhibitors (TKIs) in patients with NSCLC harbouring these uncommon mutations. Here, we reported the case of a complete metabolic response in a patient with advanced NSCLC carrying the uncommon G719A/V769M complex mutation treated with the first-line osimertinib.

Celiomesenteric trunk aneurysm.

A celiomesenteric trunk (CMT) is an extremely rare anatomic variant that consists of celiac and superior mesenteric arteries having a common origin from the aorta. CMT accounts for less than 1% of all splanchnic artery anomalies. Aneurysm involving a CMT is an even rarer vascular abnormality, and, to our knowledge, only eight cases of CMT aneurysm have been reported in literature.

Primary great saphenous vein leiomyosarcoma: report of a case.

Leiomyosarcomas rarely arise in primary veins, especially the great saphenous vein. We have found only 20 case reports of leiomyosarcoma arising in the great saphenous vein, most of which manifested as nonspecific symptoms of advanced disease, such as a palpable mass, swelling, and back or abdominal pain. We report the case of greater saphenous vein leiomyosarcoma diagnosed in a 48-year-old man with a 4-month history of an inguinal mass.