Acute esophageal necrosis following cardiac arrest: A rare and lethal syndrome with diagnostic challenges.

Introduction And Clinical Relevance: Acute esophageal necrosis (AEN) is a condition characterized by the necrosis of the distal portion of the esophageal mucosa. Risk factors predisposing to this condition are associated to compromised vascular perfusion (e.g.

Prehospital invasive arterial blood pressure monitoring in critically ill patients attended by a UK helicopter emergency medical service- a retrospective observational review of practice.

Background: Accurate haemodynamic monitoring in the prehospital setting is essential. Non-invasive blood pressure measurement is susceptible to vibration and motion artefact, especially at extremes of hypotension and hypertension: invasive arterial blood pressure (IABP) monitoring is a potential solution. This study describes the largest series to date of cases of IABP monitoring being initiated prehospital.

Lung ultrasound in ruling out COVID-19 pneumonia in the ED: a multicentre prospective sensitivity study.

Purpose: Early diagnosis of COVID-19 has a crucial role in confining the spread among the population. Lung ultrasound (LUS) was included in the diagnostic pathway for its high sensitivity, low costs, non-invasiveness and safety. We aimed to test the sensitivity of LUS to rule out COVID-19 pneumonia (COVIDp) in a population of patients with suggestive symptoms.

Combinatorial Peptide Ligand Library and two dimensional electrophoresis: new frontiers in the study of peritoneal dialysis effluent in pediatric patients.

Unlabelled: Peritoneal dialysis effluent (PDE) is a fluid resulting from the close contact of peritoneal dialysis (PD) solutions with the peritoneal membrane (PM) and represents a readily available material for the search of biomarkers of PM function or damage. Our laboratory has developed a method for the in-depth proteomic characterization of PDE, which involves Combinatorial Peptides Ligand Library (CPLL) to reduce the dynamic range of protein concentration in PDE, followed by two-dimensional electrophoresis (2-DE). In this study we applied this method to the analysis of PDE proteome obtained from 19 pediatric patients on automated peritoneal dialysis (APD) with glucose-based PD solutions.