Comparison of Drusen Volume Assessed by Two Different OCT Devices.

To compare drusen volume between Heidelberg Spectral Domain (SD-) and Zeiss Swept-Source (SS) PlexElite Optical Coherence Tomography (OCT) determined by manual and automated segmentation methods. Thirty-two eyes of 24 patients with Age-Related Macular Degeneration (AMD) and drusen maculopathy were included. In the central 1 and 3 mm ETDRS circle drusen volumes were calculated and compared.

The Effect of Speaking Valves on ICU Mobility of Individuals With Tracheostomy.

Background: Early mobilization is part of the rehabilitation process for critically ill patients and is currently considered a means of preventing ICU-acquired muscle deterioration and worsening of physical function. We sought to determine whether the use of speaking valves in tracheostomized patients would improve their mobility. We evaluated the changes in mobility performance with the use of speaking valves in tracheostomized subjects.

Quantification of retinal layer thickness changes in acute macular neuroretinopathy.

Purpose: To quantitatively evaluate retinal layer thickness changes in acute macular neuroretinopathy (AMN).

Methods: AMN areas were identified using near-infrared reflectance (NIR) images. Intraretinal layer segmentation using Heidelberg software was performed.

Retinal Ganglion Cell Layer Change in Patients Treated With Anti-Vascular Endothelial Growth Factor for Neovascular Age-related Macular Degeneration.

Purpose: To evaluate macular retinal ganglion cell thickness in patients with neovascular age-related macular degeneration (AMD) and intravitreal anti-vascular endothelial growth factor (VEGF) therapy.

Design: Retrospective case series with fellow-eye comparison.

Methods: Patients with continuous unilateral anti-VEGF treatment for subfoveal and juxtafoveal neovascular AMD and a minimum follow-up of 24 months were included.

Evaluation of scleral and corneal thickness in keratoconus patients.

Purpose: To determine whether the scleral stroma is affected as much as the corneal stroma in keratoconus.

Setting: University Eye Clinic, Bern, Switzerland.

Design: Comparative case-control study.

Senile scleral plaques imaged with enhanced depth optical coherence tomography.

Purpose: Senile scleral plaques (SSP) are sharply demarcated greyish areas located just anterior to the insertions of the horizontal rectus muscles and thus are frequently encountered during transscleral intravitreal injections. The aim of this study was to characterize SSP using enhanced depth imaging spectral domain anterior segment optical coherence tomography (OCT) in a cohort of patients attending intravitreal injection clinics.

Methods: Prospective cross-sectional study of 380 patients attending the clinic for intravitreal injections at the Department of Ophthalmology at the Bern University Hospital.