Publications by authors named "Marco Baldrighi"
Article Synopsis
- Soluble tyrosine kinase receptor Mer (sMer) and Growth arrest-specific protein 6 (Gas6) were studied to see if they could help predict mortality risk in sepsis patients upon emergency department arrival.
- The analysis of data from the Need-Speed trial showed no significant link between sMer and Gas6 levels and 7- or 30-day mortality, though both levels were higher in patients with acute kidney injury (AKI).
- While these biomarkers did not predict mortality, they were associated with AKI, thrombocytopenia, and coagulation issues in sepsis, indicating their potential role in identifying organ damage.
Background: 5A's counselling is recommended for screening and treating patients with smoking addiction. The emergency department (ED) setting might be a suitable environment for conducting interventions for smoking cessation. The present study aims to determine the feasibility and effectiveness on smoking cessation of 5A's counselling administered to ED patients by nurses.
View Article and Find Full Text PDFStudy Objective: Early risk stratification of septic patients presenting to the emergency department (ED) is challenging. The aim of the study was to evaluate the prognostic role of plasmatic sodium level (Na) derangements at ED presentation in septic patients.
Methods: According to Na at ED presentation patients were divided in eunatremic (136-145 mEq/L), hypernatremic (>145 mEq/L) and hyponatremic (<136 mEq/L).
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host-response to infections. Osteopontin (OPN) is an extracellular matrix protein involved in the inflammatory response. Our aim was to evaluate the diagnostic and prognostic performance in sepsis of a single OPN determination in the Emergency Department (ED).
View Article and Find Full Text PDFAim: To investigate the copeptin prognostic role in mild head trauma.
Methods: We enrolled 105 adult patients who entered the emergency room because of recent mild head trauma; we evaluated: clinical picture, imaging and laboratory data (including copeptin).
Results: Copeptin resulted higher in mild head trauma patients compared with controls: 29.
Introduction: Although hypovolemia remains the most relevant problem during acute decompensated diabetes in its clinical manifestations (diabetic ketoacidosis, DKA, and hyperglycemic hyperosmolar state, HHS), the electrolyte derangements caused by the global hydroelectrolytic imbalance usually complicate the clinical picture at presentation and may be worsened by the treatment itself.
Aim: This review article is focused on the management of dysnatremias during hyperglycemic hyperosmolar state with the aim of providing clinicians a useful tool to early identify the sodium derangement in order to address properly its treatment.
Discussion: The plasma sodium concentration is modified by most of the therapeutic measures commonly required in such patients and the physician needs to consider these interactions when treating HHS.
Article Synopsis
- The study evaluated Plasma Gas6 as a potential replacement for the Baveno VI criteria in assessing esophageal varices in patients with chronic hepatitis C and advanced liver disease.
- In the cohort of 160 patients, 46% had esophageal varices, with varying sizes, and 21% met the Baveno VI criteria, demonstrating a sensitivity of 94% for detecting large varices.
- The findings suggest that Plasma Gas6 levels under 45 ng/ml could serve as an effective alternative screening method when traditional elastography methods are not available.
Background And Aim Of The Work: The aim of pain management in the Emergency Department (ED) is to temporarily optimize patient quality of life by reducing acute discomfort. The goals of this study were to evaluate the intensity and location of pain experienced by patients in the ED, the time to analgesia administration in the ED, and the patient's satisfaction so to identify potential useful interventions to improve pain management.
Methods: We prospectively collected data on the intensity of pain experienced by 137 patients during their ED stays using the Visual Analog Scale (VAS) and the Numeric Rating Scale (NRS).
Article Synopsis
- * A study evaluated the effectiveness and safety of two doses of the drug tolvaptan in treating moderate to severe hyponatremia in an Emergency Department, comparing 15 mg and 7.5 mg groups.
- * Results showed that while both doses increased sodium levels, the 15 mg dose led to a quicker rise but also a higher risk of dangerous overcorrections, suggesting that the 7.5 mg dose is a safer option for treatment.