QSAR Study of -Myristoyltransferase Inhibitors of Antimalarial Agents.

Malaria is a disease caused by protozoan parasites of the genus that affects millions of people worldwide. In recent years there have been parasite resistances to several drugs, including the first-line antimalarial treatment. With the aim of proposing new drugs candidates for the treatment of disease, Quantitative Structure⁻Activity Relationship (QSAR) methodology was applied to 83 -myristoyltransferase inhibitors, synthesized by Leatherbarrow et al.