Publications by authors named "Marco Antonio Fuentes-Garcia"
Biosensors (Basel)
September 2022
Article Synopsis
- Arterial hypertension (HTN) poses a major public health issue, significantly contributing to cardiovascular diseases and kidney failure, with a specific focus on the overexpression of ENaC in human platelets as a key feature of HTN.
- In a double-blinded study with 167 participants, an innovative diagnostic assay using gold nanoparticles linked to an anti-ENaC antibody demonstrated a 62.1% success rate in identifying patients with known HTN and 59.7% in spotting previously undiagnosed cases.
- Despite some limitations in distinguishing between healthy individuals and HTN patients, this AuNP-anti-ENaC assay shows potential as a useful tool for early screening and improved management
