Determination of the Botanical Origin and Physicochemical Properties of a Propolis Sample Through an Integrated Methodology.

The growing interest in products of natural origin has led to the implementation of products such as propolis because they possess biological properties that are useful in the treatment of various ailments, so it is relevant to know the botanical origin of the physicochemical compounds that provide propolis with its biological properties. To identify the floral sources that provide resources to bees for the manufacture of propolis, several methodologies have been implemented, such as palynological analysis, which, through pollen content, has made it possible to identify the plant species that provide resources to bees. On the other hand, analysis of the physicochemical components of propolis has revealed that phenols and flavonoids are mainly responsible for the biological activity of propolis.

Botanical Origin and Biological Properties of Honey and Propolis from Cuautitlan, State of Mexico, Mexico.

Beekeeping is an activity that generates various products, mainly honey and propolis, with different biological activities that are studied extensively using various methodologies. The influence of various phenolic compounds, such as phenols and flavonoids, which are synthesized and concentrated differently in each product depending on the melliferous flora and sources of resources, on the manufacture of propolis or honey has been investigated. However, the analysis of these products has been performed separately and is outdated in time, and depending on the area and the flowering periods, different crops may be harvested.

Effect of Mexican Propolis on Wound Healing in a Murine Model of Diabetes Mellitus.

Diabetes mellitus (DM) affects the wound healing process, resulting in impaired healing or aberrant scarring. DM increases reactive oxygen species (ROS) production, fibroblast senescence and angiogenesis abnormalities, causing exacerbated inflammation accompanied by low levels of TGF-β and an increase in Matrix metalloproteinases (MMPs). Propolis has been proposed as a healing alternative for diabetic patients because it has antimicrobial, anti-inflammatory, antioxidant and proliferative effects and important properties in the healing process.

Activity of propolis from Mexico on the proliferation and virulence factors of Candida albicans.

Background: This research evaluated the anti-Candida albicans effect of Mexican propolis from Chihuahua. Chemical composition of the ethanolic extract of propolis was determined by GC-MS, HPLC-DAD, and HPLC-MS. The presence of anthraquinone, aromatic acid, fatty acids, flavonoids, and carbohydrates was revealed.

Essential Oil of Promotes Cell Migration on Fibroblasts: In Vitro Assays.

Essential oils (EOs) are complex mixtures of volatile natural compounds. We have extensively studied the EO of , which demonstrates antibacterial, antifungal, anti-inflammatory, and wound-healing activities. The objective of this work was to determine the effect of this EO on fibroblast migration in a three-dimensional in vitro model.

Anti-Inflammatory and Histological Analysis of Skin Wound Healing through Topical Application of Mexican Propolis.

Skin wound healing is a complex biochemical process of tissue repair and remodeling in response to injury. Currently, the drugs used to improve the healing process are inaccessible to the population, are costly, and have side effects, making the search for new treatment alternatives necessary. Propolis is a natural product produced by bees that is widely recognized and used in folk medicine for its multiple biomedical activities.

Biological Activity of Essential oil and the Roles of Its Chemical Components in the Wound Healing Process.

Essential oils are composed of terpenes, some of which have properties related to healing. essential oil (BSEO) is used to heal superficial wounds. However, there have been no studies verifying this property.

Antimicrobial activity of the methanolic leaf extract of Prosopis laevigata.

The appearance of antimicrobial-resistant pathogens has highlighted the need to search for new compounds that can effectively combat infectious diseases. A potential source of these compounds are the secondary metabolites of species that have been reported as effective traditional treatments of such diseases. Prosopis laevigata is a medicinal plant, and its chemical constituents have shown potential antimicrobial activity.

Effect of the Essential Oils of and and Five Pure Compounds on the Mycelium, Spore Production, and Germination of Species of .

The genus causes many diseases in economically important plants. Synthetic agents are used to control postharvest diseases caused by , but the use of these synthetic agents generates several problems, making it necessary to develop new alternative pesticides. Essential oils can be used as a new control strategy.

The Wound-Healing Effect of Mango Peel Extract on Incision Wounds in a Murine Model.

can generate up to 60% of polluting by-products, including peels. However, it has been shown that flavonoids and mangiferin are mainly responsible for the antioxidant, anti-inflammatory, and antibacterial activities closely related to the wound-healing process. The chemical composition of MEMI (methanolic extract of ) was analyzed by HPLC-DAD, as well as concentrations of total phenol (TPC) and flavonoids (TFC) and antioxidant activity (SA).

Essential oils of Bursera morelensis and Lippia graveolens for the development of a new biopesticides in postharvest control.

Fruit and vegetable crops that are not consumed immediately, unlike other agricultural products, require economic and time investments until they reach the final consumers. Synthetic agrochemicals are used to maintain and prolong the storage life of crops and avoid losses caused by phytopathogenic microorganisms. However, the excessive use of synthetic agrochemicals creates health problems and contributes to environmental pollution.

Propolis and Its Gastroprotective Effects on NSAID-Induced Gastric Ulcer Disease: A Systematic Review.

Gastric ulcer disease induced by the consumption of NSAIDs is a major public health problem. The therapy used for its treatment causes adverse effects in the patient. Propolis is a natural product that has been used for the treatments of different diseases around the world.

Wound Healing Activity of α-Pinene and α-Phellandrene.

is used in Mexican folk medicine to treat wounds on the skin. Recently, it was shown that the essential oil (EO) of has wound healing activity, accelerating cutaneous wound closure and generating scars with good tensile strength. α-pinene (PIN) and α-phellandrene (FEL) are terpenes that have been found in this EO, and it has been shown in different studies that both have anti-inflammatory activity.

Pax Latex Exhibits Wound-Healing Effect in Normal and Diabetic Mice.

is an endemic species of Mexico. Its latex is used to treat wounds, scarring, oral infections, and loose teeth. To date, there are no studies that validate at a morphological level a wound-healing use in diabetes.

Evaluation of the gastroprotective effects of Chihuahua propolis on indomethacin- induced gastric ulcers in mouse.

The aim of this work was to evaluate the gastroprotective activity of a Mexican propolis on indomethacin-induced gastric ulcers in a mouse model. The following contents of the ethanolic extract of propolis of Chihuahua (EEPCh) were determined: antioxidant activity (SA), total phenolic content (TPC), total flavonoid content (TFC), and chemical composition by HPLC-DAD and HPLC-MS, as well as acute toxicity by OECD Guideline 423. Gastric lesions were induced by intragastric indomethacin treatment in male ICR mice.

Anti-Inflammatory and Antioxidant Activities of the Methanolic Extract of Bark Reduces the Severity of Ulcerative Colitis in a Chemically Induced Colitis Model.

is a plant used in traditional Mexican medicine to treat different gastrointestinal problems. Here, we investigated the effects of a methanolic extract in DSS-induced colitis mice. Ulcerative colitis (UC) was induced by administering 4% DSS in drinking water to female BALB/c mice.

Wound Healing Activity of the Essential Oil of , in Mice.

is used in Mexican folk medicine to treat wounds on the skin. It is an endemic tree known as "aceitillo", and the antibacterial and antifungal activity of its essential oil has been verified; it also acts as an anti-inflammatory. All of these reported biological activities make the essential oil of a candidate to accelerate the wound-healing process.

Novel CB1 receptor antagonist BAR-1 modifies pancreatic islet function and clinical parameters in prediabetic and diabetic mice.

Backgrouds: Cannabinoid receptor antagonists have been suggested as a novel treatment for obesity and diabetes. We have developed a synthetic cannabinoid receptor antagonist denominated BAR-1. As the function and integrity of a β-cell cellular structure are important keys for diabetes onset, we evaluated the effects of pharmacological administration of BAR-1 on prediabetic and diabetic rodents.

Comparison of Biological Properties of Two Medicinal Extracts of the Tehuacan-Cuicatlan Valley.

In the Valley of Tehuacan-Cuicatlan, and are located and are used in traditional medicine. In this research, several biological properties were evaluated. The methanol extracts of (MeCp) and (MeBm) were obtained by maceration.

Anti-Candida Activity of Bursera morelensis Ramirez Essential Oil and Two Compounds, α-Pinene and γ-Terpinene-An In Vitro Study.

The candidiasis caused by is a public health problem. The abuse of antifungals has contributed to the development of resistance. has demonstrated antibacterial and antifungal activities.

Protective Effect of Amphipterygium adstringens Extract on Dextran Sulphate Sodium-Induced Ulcerative Colitis in Mice.

Amphipterygium adstringens is an endemic species in Mexico commonly known as "cuachalalate." Healers to treat gastritis, gastric ulcers, and gastrointestinal cancer have traditionally used the bark. We investigated the effects of alcoholic extract of A.

Evaluation of the medicinal properties of Cyrtocarpa procera Kunth fruit extracts.

Background: The fruit of Cyrtocarpa procera is used to treat stomach diseases by people living in San Rafael, Coxcatlan, Puebla. This work investigated the antibacterial, antioxidant, cytotoxic and anti-inflammatory activities of the fruit produced by this species.

Methods: Methanol extract was obtained by maceration.

Naegleria fowleri: contact-dependent secretion of electrondense granules (EDG).

The free living amoeba Naegleria fowleri is pathogenic to humans but also to other mammalians. These amoebae may invade the nasal mucosa and migrate into the brain causing cerebral hemorrhagic necrosis, a rapidly fatal infection. Knowledge of the cytolytic mechanism involved in the destruction of brain tissues by Naegleria trophozoites is limited.

Naegleria fowleri glycoconjugates with residues of α-D-mannose are involved in adherence of trophozoites to mouse nasal mucosa.

We analyzed the possible role of glycoconjugates containing α-D-mannose and α-D-glucose residues in adherence of trophozoites to mouse nasal epithelium. Trophozoites incubated with 20 μg of one of three different lectins which preferentially recognized these residues were inoculated intranasally in Balb/c mice. Mouse survival was 40% with Pisum sativum and Canavalia ensiformis and 20% with Galanthus nivalis amebic pretreatment, compared with 0% survival for control animals administered trophozoites without pretreatment.

Nitric oxide production and nitric oxide synthase immunoreactivity in Naegleria fowleri.

Free-living ameba Naegleria fowleri produces an acute and fatal infectious disease called primary amebic meningoencephalitis (PAM), whose pathophysiological mechanism is largely unknown. The aim of this study was to investigate the role of nitric oxide (NO) in PAM. Although NO has a cytotoxic effect on various parasites, it is produced by others as part of the pathology, as is the case with Entamoeba histolytica.