Opioids, stimulants, and depressant drugs in fifteen Mexican Cities: A wastewater-based epidemiological study.

Background: Monitoring drug use in México is a challenge due to emerging drugs and rapid changes in consumption patterns. The temporal and geographical patterns of cocaine, methamphetamine, amphetamine, MDMA, cannabis, heroin, ketamine, and fentanyl were examined in Mexican cities using wastewater-based epidemiology (WBE).

Methods: 105 daily composite wastewater samples were collected from sewage treatment plants in fifteen Mexican cities.

Human papillomavirus type 16 variants in cervical intraepithelial neoplasia and invasive carcinoma in San Luis Potosí City, Mexico.

Background: In San Luis Potosí City cervical infection by human papillomavirus type 16 (HPV16) associated to dysplastic lesions is more prevalent in younger women. In this work HPV16 subtypes and variants associated to low-grade intraepithelial lesions (LSIL), high-grade intraepithelial lesions (HSIL) and invasive cervical cancer (ICC) of 38 women residing in San Luis Potosí City were identified by comparing their E6 open reading frame sequences.

Results: Three European (E) variants (E-P, n = 27; E-T350G, n = 7; E-C188G, n = 2) and one AA-a variant (n = 2) were identified among the 38 HPV16 sequences analyzed.