Pharmacokinetic interactions between depot medroxyprogesterone acetate and combination antiretroviral therapy.

Objective: To evaluate the effect of an antiretroviral (ARV) therapy regimen containing zidovudine (AZT), lamivudine (3TC), and efavirenz (EFV) on the pharmacokinetics of depot medroxyprogesterone acetate (DMPA).

Design: Open-label, nonrandomized, clinical trial.

Setting: University hospital clinic.