Publications by authors named "Marcis Scroger"
Individuals with alcohol use disorder (AUD) struggle with inhibitory control, decision making, and emotional processing. These cognitive symptoms reduce treatment adherence, worsen clinical outcomes, and promote relapse. Neuroimmune activation is a key factor in the pathophysiology of AUD, and targeting this modulatory system is less likely to produce unwanted side effects compared to directly targeting neurotransmitter dysfunction.
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- Hyperkatifeia refers to emotional distress and is recognized as a significant factor contributing to addiction, particularly in the context of alcohol use disorders (AUD).
- Negative life experiences can trigger increased alcohol consumption, leading to the development of AUD, with hyperkatifeia often emerging during withdrawal and promoting relapse.
- The review highlights the role of norepinephrine and its dysfunction in AUD, emphasizing the need for targeted treatments and indicating that certain populations, like women and those with comorbid conditions, may particularly benefit from these therapies.