Multimodal management of a persistent labial hemangioma: a case report.

Hemangiomas are benign vascular tumors that are relatively unusual in the oral cavity. The management of labial hemangiomas may be challenging for functional and esthetic reasons. In the present case, a 12-year-old boy with a large congenital hemangioma in the area of the upper lip was referred due to esthetic concerns and a history of treatment failure.

Clinicopathological Analysis of Oral Paracoccidioidomycosis in Women.

Unlabelled: Paracoccidioidomycosis (PCM) is a deep systemic mycosis caused by Paracoccidioides brasiliensis. PCM affects predominantly men in their fifth and sixth decades of life, with low prevalence in women. The reasons for this discrepancy are not fully understood, but oestrogen may influence the transformation of the fungus and modulate the immune response.

Radiation-induced changes in salivary metabolite profile and pathways in head and neck cancer patients.

Introduction: This longitudinal study assessed the salivary metabolic profile in patients with head and neck cancer (HNC) treated with radiotherapy (RT). This study aims to investigate salivary metabolites and biological oral pathways induced by RT.

Methods: Clinical data and unstimulated whole-mouth saliva (USWMS) were obtained from 45 HNC patients before, during, and one week after the RT.

Exploring mandibular buccal bifurcation cysts: a case series and a comprehensive literature review.

Objective: The objective of this study was to explore the clinical and microscopic findings of mandibular buccal bifurcation cysts (MBBCs) in an original case series and to perform a literature review of this lesion.

Study Design: Paraffin-embedded tissue blocks from patients microscopically diagnosed with MBBCs were retrieved from 4 oral and maxillofacial pathology archives. Data, including clinical, radiographic, and microscopic characteristics, treatments used, and follow-up status, were collected from the pathology records.

Calcifying odontogenic cyst: A detailed international multicentric study.

Objective: To elucidate the histopathological, immunohistochemical, and ultrastructural characteristics of a large series of calcifying odontogenic cysts (COCs).

Study Design: This was a multicenter cross-sectional retrospective study of seven oral pathology department laboratories from four countries. Clinical, demographic, and radiographic data of the patients were collected.

Artificial intelligence in healthcare applications targeting cancer diagnosis-part II: interpreting the model outputs and spotlighting the performance metrics.

Background: The lack of standardized performance assessment metrics and the inconsistent reporting of results can lead to the presentation of overly optimistic outcomes that fail to accurately represent key aspects of the Machine Learning framework and may not align with real-world clinical needs.

Methods: This conceptual review of the literature compiled the theoretical basis for performance analysis of binary and multiclass models.

Results: Accuracy and error rates are straightforward but not ideal if dataset is imbalanced.

Artificial intelligence in healthcare applications targeting cancer diagnosis-part I: data structure, preprocessing and data organization.

Background: Machine learning techniques hold significant potential to support the diagnosis and prognosis of diseases. However, the success of these approaches is heavily dependent on rigorous data acquisition, preprocessing and data organization.

Methods: This article reviews the literature to evaluate key factors in dataset construction, focusing on data structure, preprocessing, and data organization, particularly in the context of imaging data.

Oral Kaposi sarcoma in Brazil: a case series of 40 patients highlighting a significant health burden.

Objective: The aim of this study was to provide a comprehensive clinicopathological analysis of oral Kaposi sarcoma (KS) cases and examine its relationship with HIV-related immunosuppression.

Study Design: Paraffin-embedded tissue blocks of patients microscopically diagnosed with oral KS were retrieved from three oral and maxillofacial pathology files. Data including clinical, laboratory, microscopic and immunohistochemical findings and treatment employed were retrieved.

Comparative analysis of clinicopathological characteristics in young and elderly patients with oral squamous cell carcinoma: a retrospective study in Northeastern Brazil.

The aim of this study was to perform a clinicopathological analysis of oral squamous cell carcinoma (OSCC) in young patients from the northeast of Brazil and compare with elderly individuals. This retrospective study reviewed 104 OSCC cases from 2000 to 2015, focusing on patients under 40 and over 60 at diagnosis. Forty-two patients under 40 years old (40.

Plasmablastic Lymphoma in the Submandibular Region Diagnosed by FNAC: A Case Report and Literature Review.

Objective: This study aims to provide a literature review of FNAC-diagnosed plasmablastic lymphoma (PBL) cases and present a case of PBL in an HIV patient diagnosed by FNAC.

Methods: A literature review was conducted across eight databases to compile information on FNAC-diagnosed PBL cases without restricting the site of involvement.

Results: The literature review included 23 PBL, with 13 (56.

Deep Convolutional Neural Network for Accurate Classification of Myofibroblastic Lesions on Patch-Based Images.

Objective: This study aimed to implement and evaluate a Deep Convolutional Neural Network for classifying myofibroblastic lesions into benign and malignant categories based on patch-based images.

Methods: A Residual Neural Network (ResNet50) model, pre-trained with weights from ImageNet, was fine-tuned to classify a cohort of 20 patients (11 benign and 9 malignant cases). Following annotation of tumor regions, the whole-slide images (WSIs) were fragmented into smaller patches (224 × 224 pixels).

Development and Evaluation of a Convolutional Neural Network for Microscopic Diagnosis Between Pleomorphic Adenoma and Carcinoma Ex-Pleomorphic Adenoma.

Aims: To develop a model capable of distinguishing carcinoma ex-pleomorphic adenoma from pleomorphic adenoma using a convolutional neural network architecture.

Methods And Results: A cohort of 83 Brazilian patients, divided into carcinoma ex-pleomorphic adenoma (n = 42) and pleomorphic adenoma (n = 41), was used for training a convolutional neural network. The whole-slide images were annotated and fragmented into 743 869 (carcinoma ex-pleomorphic adenomas) and 211 714 (pleomorphic adenomas) patches, measuring 224 × 224 pixels.

Head and Neck Cancer in Pan-American Notable People: An International Survey.

The study of notable people as advocates for raising cancer awareness began in the latter decades of the 20th century. This research aimed to identify Pan-American notable people with head and neck cancer (HNC) and to explore senior health professionals' perspectives on communicating stories of notable patients with HNC to promote prevention. A cross-sectional survey was conducted using an online questionnaire designed in REDCap and administered to 32 senior health professionals with long-standing academic and clinical backgrounds in HNC.

Mapping oral medicine (stomatology) and oral and maxillofacial pathology international organizations: a scoping review of global data and historical analysis.

Objectives: To describe the historical evolution and dissemination of the Oral Medicine and Oral and Maxillofacial Pathology international societies and associations across the globe, and to provide insights into their significant contributions toward oral health promotion.

Study Design: This review was conducted in accordance with the JBI Scoping Review Methodology Group guidance. The reporting followed the Preferred Reporting Items for Systematic Reviews extension for Scoping Reviews (PRISMA-ScR).

Local anesthesia nerve block for managing burning mouth syndrome: a scoping review.

Objective: To assess the clinical scenarios in which nerve blocks are employed in the context of burning mouth syndrome (BMS).

Study Design: This scoping review followed the PRISMA-ScR. A protocol was generated on Open Science Framework.

Conspiracy of Silence in Head and Neck Cancer Diagnosis: A Scoping Review.

Cancer disclosure represents a complex healthcare dynamic. Physicians or caregivers may be prompted to withhold diagnosis information from patients. This study aims to comprehensively map and synthesize available evidence about diagnosis nondisclosure regarding head and neck cancer (HNC) patients.