The Chitosan-Based System with Extract for the Local Treatment of Vaginal Infections.

, as a flavone-rich source, exhibits antibacterial, antifungal, antioxidant, and anti-inflammatory activity. It may be used as a therapeutic agent to treat various diseases, including vaginal infections. In this study, six binary mixtures of chitosan with stable lyophilized extract were obtained and identified by spectral (ATR-FTIR, XRPD) and thermal (TG and DSC) methods.

Use of ex utero intrapartum treatment procedure in fetal neck and high airway anomalies - report of four clinical cases.

Purpose: To present antenatal management and use of ex utero intrapartum treatment (EXIT) in different fetal neck and high airway anomalies.

Material And Methods: We have presented four different cases of fetal neck or airway pathology which were indications for EXIT, at our department.

Results: In three cases of fetal neck tumors, the primary precise antenatal diagnoses of tumors were confirmed after birth.

Complement inhibitory proteins expression in placentas of thrombophilic women.

Factors controlling complement activation appear to exert a protective effect on pregnancy. This is particularly important in women with thrombophilia. The aim of this study was to determine the transcript and protein levels of complement decay-accelerating factor (DAF) and membrane cofactor protein (MCP) in the placentas of women with acquired and inherited thrombophilia.

[Incidence of hereditary thrombophilia in women with pregnancy loss in multi-center studies in Poland].

Aim: The aim of this study was to estimate the prevalence of factor V Leiden and prothrombin gene G20210A mutation among women with pregnancy loss in Poland.

Material And Methods: we analyzed a group of 396 women (mean age of 30.4 (+/- 4.

[Frequency of antiphospholipid syndrome in women with pregnancy loss in multicenter study in Poland].

The Aim: The aim of the study was the analysis of antiphospholipid syndrome frequency in Polish women with pregnancy loss.

Material And Methods: We analyzed 352 women with average age of 31.4 (+/- 4.

[Histologic changes in placenta and chorion of women with antiphospholipid syndrome and inherited thrombophilia].

Background: The aim of the study was a histologic evaluation of placentas and chorions from pregnancies complicated by antiphospholipid syndrome (APS) and inherited thrombophilia in women treated with anticoagulants and in a group of women without the anticoagulant treatment.

Material: 24 placentas from 18 patients with acquired and inherited thrombophilia and 23 chorions from 19 miscarriages in women with the same diagnosis were included in the study There were 33 chorions from miscarriages from healthy women and 25 placentas from uneventful pregnancies in the control group. Biopsies from placentas and chorions were stained with eosin and hematoxylin and evaluated for the presence of villous thrombosis, fibrin deposits, intraplacental hematomas, thrombosis in fetal circulation and other histological findings.

[The management of ovarian tumors in pregnancy and perinatal outcome].

Aim: The pregnancy course in women with gestational ovarian mass and conservative or operative management.

Material And Methods: In retrospective analysis we analyzed 83 pregnant women with ovarian mass diagnosed between 2002-2009. We considered the following factors: gestational age when diagnosed, ultrasound picture, clinical symptoms, level of CA 125, treatment used, pathologic results and pregnancy outcome.

[Frequency of antiphospholipid antibodies and antiphospholipid syndrome in women with recurrent miscarriages].

Objectives: The aim of the study was to evaluate antiphospholipid antibodies and antiphospholipid syndrome frequency (according to current criteria) in women with recurrent miscarriages.

Material And Methods: We examined 105 women diagnosed due to recurrent miscarriages. Patients were divided into 2 groups: with early recurrent miscarriages and with late recurrent miscarriages.

[Do abnormal results of Doppler examinations in fetuses with growth restriction increase the frequency of postnatal complications of the central nervous system and gastrointestinal tract?].

Objectives: The aim of the work was to assess the correlations between the results of antenatal Doppler examinations in fetuses with growth restriction (IUGR) and the frequency of postnatal complications of central nervous system and gastrointestinal tract.

Material And Methods: 47 pregnant women and 47 fetuses and newborns from singleton pregnancies with diagnosed intrauterine growth restriction. Two groups of fetuses (newborns) were distinguished based on serial Doppler examinations of fetal umbilical and middle cerebral arteries: 1) newborns with IUGR and abnormal results of antenatal Doppler examinations (group 1); 2) newborns with IUGR and normal results of antenatal Doppler examinations (group 2).

[Frequency of antiphospholipid antibodies and factor V (G1691A), prothrombin (G20210A) gene polimorphism among women with pregnancy complications].

Thrombophilia these days is a subject of many medical research including obstetric and gynecology where causing feto-maternal complications. In women predispose to venous thromboembolism in high risk situation like pregnancy, puerperium, operation, prolonged bed rest or hormonal treatment. For fetal complication account miscarriages, intrauterine deaths, IUGR, and for maternal account premature placental separation and severe preeclampsia.