Lipid biomarkers in colorectal cancer, with particular emphasis on exosomes - current status and future inferences.

Introduction: Colorectal cancer (CRC) is one of the most deadly cancers on a global scale. Diagnosis of CRC is challenging and it is often detected at a late stage. Identification of relevant biomarkers could lead to the development of effective diagnostic methods for CRC.

Polarisation compensation in non-planar image-rotating OPO ring resonators.

Non-planar image-rotating OPO ring resonators necessitate polarisation compensation in contrast to their planar counterparts. This is essential for maintaining phase matching conditions for non-linear optical conversion in the resonator during each cavity round trip. In this study, we examine the polarisation compensation and its impact on the performance of two types of non-planar resonators: RISTRA with a 2 image rotation and FIRE with a fractional image rotation (2 fraction).

Evaluation of a Fatigue Detector Using Eye Closure-Associated Indicators Acquired from Truck Drivers in a Simulator Study.

This paper presents a camera-based prototype sensor for detecting fatigue and drowsiness in drivers, which are common causes of road accidents. The evaluation of the detector operation involved eight professional truck drivers, who drove the truck simulator twice-i.e.

Beam quality and efficiency of ns-pulsed high-power mid-IR ZGP OPOs compared in linear and non-planar ring resonators.

We compare the performance of ns-pulsed mid-infrared optical parametric oscillators (OPOs) based on ZGP crystals in a simple linear cavity and two non-planar image-rotating resonators. Our 2 μm pump source is a 68 W 10 kHz diffraction limited Ho:LLF MOPA system. In a linear cavity, it allows us to generate up to 38 W of the total average power with M<2.

Effects of pump pulse energy and repetition rate on beam quality in a high-power mid-infrared ZnGeP OPO.

We report on changes of beam quality with rising pump pulse energy and repetition rate in a high-power mid-infrared ZnGeP (ZGP) OPO in a non-planar cavity. The ZGP OPO generates 25 W in 3 - 5 μm pumped by a 10 kHz Q-switched Ho:LLF MOPA system at 2 μm. The beam quality factor increases from nearly diffraction-limited at OPO threshold to a M = 1.

A single-atom 3D sub-attonewton force sensor.

Forces drive all physical interactions. High-sensitivity measurement of the effect of forces enables the quantitative investigation of physical phenomena. Laser-cooled trapped atomic ions are a well-controlled quantum system whose low mass, strong Coulomb interaction, and readily detectable fluorescence signal make them a favorable platform for precision metrology.

Dual Hg-Rb magneto-optical trap.

We present a two-species laser cooling apparatus capable of simultaneously collecting Rb and Hg atomic gases into a magneto-optical trap (MOT). The atomic sources, laser system, and vacuum set-up are described. While there is a loss of Rb atoms in the MOT due to photoionization by the Hg cooling laser, we show that it does not prevent simultaneous trapping of Rb and Hg.

Preliminary Results of the LF/HF Ratio as an Indicator for Estimating Difficulty Level of Flight Tasks.

Introduction: The main aim of this study was to differentiate the magnitude of a pilot's heart rate variability (HRV) when performing assisted and unassisted flights, as well as simple and complex flight tasks.

Methods: Cardiac monitoring in flights was carried out using a compact, mobile ECG recorder. A frequency analysis of the heart rate (HR) signal was performed to determine the ratio of low-frequency spectral power (LF) to high-frequency spectral power (HF).