Publications by authors named "Marcin Nylec"
Article Synopsis
- The study investigates the significance of preoperative inflammation markers, specifically neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR), in predicting the 1-year outcomes of patients who underwent orthotopic liver transplantation (OLTx).
- It found that high preoperative neutrophil levels, as well as certain conditions like acute liver failure and autoimmune hepatitis, significantly increase the risk of graft loss and patient death within the first year post-transplant.
- The research highlights NLR above 5.48 as a strong predictor of these negative outcomes while suggesting the need for further investigation into the impact of systemic inflammation and immunity on long-term liver function.
Objective: The aim of the study was to analyse relationships between plasma apelin-36 and apelin-12 levels, nutritional status, insulin resistance and hormonal disturbances, as well as plasma adiponectin, leptin and resistin concentrations in PCOS women.
Study Design Patients And Measurements: A cross-sectional study involving 87 PCOS (48 obese) and 67 non-PCOS women (36 obese). Anthropometric parameters and body composition were determined.
Introduction: Visfatin is an adipokine secreted by visceral adipose tissue with insulin-mimetic properties. Higher circulating visfatin levels were reported in type 2 diabetes. The aim of this study was to analyse circulating visfatin and insulin levels and the visfatin/insulin ratio in obese women with and without metabolic syndrome (MetS).
View Article and Find Full Text PDFBackground: Experimental studies have shown that tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6) downregulate visfatin gene expression in adipocytes. On the other hand, the induction of cytokine production by visfatin in leucocytes and monocytes has also been described.
Aim: To assess the possible interrelation between plasma concentrations of visfatin and TNF-α and TNF soluble receptor in obese women fulfilling, or not, the criteria of metabolic syndrome (MS).
Appetite control is a complex process regulated by both neurotransmitters, such as: appetite- increasing neuropeptide Y (NPY), Agouti related peptide (AgRP), orexins A and B, as well as appetite-suppressing propiomelanocortin (POMC) and a peptide (CART) which transcription is regulated by cocaine and amphetamine. In addition, other factors are involved such as hormones of the alimentary tract (appetite-stimulating ghrelin and appetite-decreasing cholecystokinin, peptide YY, glucagon like peptide-1, oxyntomodulin, pancreatic peptide, enterostatin and amylin). In this process participates also leptin, an appetite-suppressing hormone produced by adipocytes.
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