Accelerated Aging Effect on the Stability of the 3D-Printed Biodegradable Implant for Bone Defect Repairs.

This article presents an evaluation of the accelerated aging impact on the structural properties of biodegradable PLA/HAp implants produced using 3D printing technology for use in traumatic bone defect repairs in individual patients. The designed biodegradable implants were sterilized with a radiation dose of 25 ± 0.99% kGy, then exposed to an accelerated aging process.

Effect of the Advanced Cranial and Craniofacial Implant Fabrication on Their Degradation Affinity.

Biodegradable craniofacial and cranial implants are a new aspect in terms of reducing potential complications, especially in the long term after surgery. They are also an important contribution in the field of surgical reconstructions for children, for whom it is important to restore natural bone in a relatively short time, due to the continuous growth of bones. The aim of this study was to verify the impact of the technology on biodegradability and to estimate the risk of inappropriate implant resorption time, which is an important aspect necessary to select prototypes of implants for in vivo testing.

Design of New Concept of Knitted Hernia Implant.

A knitted implant, unilaterally modified with plasma-assisted chemical-vapor deposition (PACVD), and with a nano-layer of fluorine derivative supplementation, for reducing the risk of complications related to adhesions, and the formation of a thick postoperative scar was prepared. The biological evaluation of designed or modified medical devices is the main aspect of preclinical research. If such studies use a medical device with prolonged contact with connective tissue (more than 30 days), biocompatibility studies require a safety assessment in terms of toxicity in vitro and in vivo, allergenicity, irritation, and cancerogenicity, reproductive and developmental toxicity.

Multi-Criterial Analysis Tool to Design a Hybrid Ballistic Plate.

The presented research focuses on the concept of an advanced ballistic personal protection design, taking into account safety as well as performance requirements. The application of the multi-criterial analysis (MCA) allows for a comprehensive comparison of all the properties of materials and to select the optimal personal ballistic protection system, considering their mechanical and ballistic properties. The newly developed hybrid ballistic composites, consisting of two or three various components (variations of ballistic and/or non-ballistic textiles; hybrid ballistic plates-HBP), were evaluated via a multi-criterial analysis that considered a wide range of properties, describing behavior and safety usage, as well as the economical aspect of their fabrication.

The Influence of a Knitted Hydrophilic Prosthesis of Blood Vessels on the Activation of Coagulation System-In Vitro Study.

The replacement of affected blood vessels of the polymer material can cause imbalances in the blood haemostatic system. Changes in blood after the implantation of vascular grafts depend not only on the chemical composition but also on the degree of surface wettability. The Dallon H unsealed hydrophilic knitted vascular prosthesis double velour was assessed at work and compare with hydrophobic vascular prosthesis Dallon.

Design of New-Generation Usable Forms of Topical Haemostatic Agents Containing Chitosan.

Designing usable forms of topical haemostatic agents is the most important activity during the design process, resulting in strengthened functional properties of the final medical devices. This study aimed to propose indications for a research programme based on risk management supporting the development of two usable forms of a topical haemostatic agent: chitosan/alginate lyophilized foam and chitosan/alginate impregnated gauze. Both of the usable forms of the topical haemostatic agent, being the main part of the modified combat gauze, were fabricated using the chitosan/alginate complex.

Knitting for heart valve tissue engineering.

Knitting is a versatile technology which offers a large portfolio of products and solutions of interest in heart valve (HV) tissue engineering (TE). One of the main advantages of knitting is its ability to construct complex shapes and structures by precisely assembling the yarns in the desired position. With this in mind, knitting could be employed to construct a HV scaffold that closely resembles the authentic valve.

Synthetic vascular prostheses.

Polyethyleneterephthalate (PET), and to a lesser extent Teflon have become the major synthetic grafting material. Unlike nylon, Ivalon, and Vinyon-N which lose their tensile strength after implantation, PET and Teflon remain essentially unchanged even after long periods. TRICOMED S.