Calendula glycolic extract enhances wound healing of alginate hydrogel.

Purpose: To assess the cytotoxicity and wound healing properties of an alginate hydrogel containing calendula glycolic extract.

Methods: Cell viability in murine fibroblasts (3T3 cells) was evaluated using MTT and SRB assays. The wound healing effect was tested in an incisional wound model on 50 female Wistar rats, divided into two groups: rats treated with alginate hydrogel (n = 25), and rats treated with calendula-alginate hydrogel.

Use and filling out of the child health booklet among beneficiaries of the Bolsa Família Program in Salvador-Bahia, Brazil: a cross-sectional study, 2023.

Objective: To compare child health booklet (CHB) use and filling out among mothers who were or were not Bolsa Família Program (BFP) beneficiaries.

Methods: Cross-sectional study with mothers of children <6years attending health centers in Salvador, Bahia, Brazil, between January-February/2023. The CHB was evaluated regarding its use (having a CHB, having it in hand, and having read it) and filling out (growth curves, development monitoring forms, and vaccination completeness).

Impact of Buriti Oil from Palm Tree on the Rheological, Thermal, and Mechanical Properties of Linear Low-Density Polyethylene for Improved Sustainability.

Recent advancements highlight the utilization of vegetable oils as additives in polymeric materials, particularly for replacing conventional plasticizers. Buriti oil (BO), extracted from the Amazon's palm tree fruit, boasts an impressive profile of vitamins, minerals, proteins, carotenoids, and tocopherol. This study investigates the impact of incorporating buriti oil as a plasticizer in linear low-density polyethylene (LLDPE) matrices.

The end of an entire biome? World's largest wetland, the Pantanal, is menaced by the Hidrovia project which is uncertain to sustainably support large-scale navigation.

The resurgent navigation project known as the Hidrovia Paraguay-Paraná threatens the integrity of the Pantanal, the world's largest wetland, which is considered a biome of its own. Intensive barge navigation is intended to transport crops (soybean, sugar, corn) and cement, iron and manganese from areas of production in Brazil, Paraguay and Bolivia to the oceanic ports of the Plata River. This short communication assembles the information available on the potential impacts of the planned deepening of the natural channel of the Paraguay River in its ~700 km-long upper section.

Kidney replacement therapy in COVID-19-Related acute kidney injury: The impact of timing on mortality.

The objective of this study was to determine the impact of the timing of KRT, dichotomized by a temporal criterion or by creatinine level, in patients with COVID-19-related AKI. This was a retrospective study involving 512 adult patients admitted to the ICU. All participants had laboratory-confirmed COVID-19 and a confirmed diagnosis of AKI.

Development and content validation of a risk classification instrument.

Objective: Develop and validate the content of an instrument for patient risk classification in emergency services of Primary Health Care.

Method: The study included two stages: item generation and content validity. A literature review and retrospective analysis of medical records were conducted to create the instrument items.

The resistome of the food chain: A One Health perspective.

Antimicrobial resistance (AMR) represents a significant global health problem which challenges Sustainable Development Goal 3 of the United Nations, with growing concerns about the possibility of AMR transmission through the food chain. The indiscriminate use of antimicrobials for the treatment of food production animals and for agricultural crop improvement, in addition to the direct discharge of livestock farm residues to sewage and the use of animal manure in agriculture, are among the factors that can facilitate the selection and transmission of AMR throughout the food chain. The study of food microbiomes has been boosted by the advent of next-generation sequencing techniques, which have enabled gaining in-depth understanding of the diversity of antimicrobial resistance genes present in food and associated environments (the so-called resistome).

Social representations of tuberculosis by people with the disease.

Objective: To understand the social representations of people with tuberculosis about the disease and its implications for following treatment.

Method: A descriptive, qualitative study based on the Theory of Social Representations. It was conducted in a municipal health unit in the city of Belém.

Clinical outcomes and prognostic factors of head and neck squamous cell carcinoma: a ten-year follow-up study.

Traditional guidelines for determining the prognosis of patients with head and neck squamous cell carcinoma (HNSCC) are used to make therapeutic decisions. However, only 50% of the patients had lived for more than five years. The present study aimed to analyze the correlation of traditional prognostic factors such as tumor size, histological grading, regional metastases, and treatment with the survival of patients with HNSCC.

Contribution of public oral pathology services to the diagnosis of oral and oropharyngeal cancer in Brazil.

This study aimed to evaluate the contribution of oral and maxillofacial pathology laboratories (OMPLs) in Brazilian public universities to the diagnosis of lip, oral cavity, and oropharyngeal squamous cell carcinoma (SCC). A cross-sectional study was performed using biopsy records from a consortium of sixteen public OMPLs from all regions of Brazil (North, Northeast, Central-West, Southeast, and South). Clinical and demographic data of patients diagnosed with lip, oral cavity, and oropharyngeal SCC between 2010 and 2019 were collected from the patients' histopathological records.

Nursing experiences in specialized services in child and adolescent mental health: a systematic review of qualitative studies.

Objective: to synthesize evidence from qualitative studies on nursing experiences regarding child and adolescent mental health care in specialized services.

Method: a systematic review with meta-synthesis of qualitative studies according to JBI guidelines. CINAHL, EMBASE, MEDLINE, LILACS, PSYCinfo, Scopus and Web of Science databases were used.

Biological effects of -farnesol in .

Introduction: Farnesol, derived from farnesyl pyrophosphate in the sterols biosynthetic pathway, is a molecule with three unsaturations and four possible isomers. predominantly secretes the , -farnesol (, -FOH) isomer, known for its role in regulating the virulence of various fungi species and modulating morphological transition processes. Notably, the evolutionary divergence in sterol biosynthesis between fungi, including , and trypanosomatids resulted in the synthesis of sterols with the ergostane skeleton, distinct from cholesterol.

Mental suffering in family daily life: a temporal journey according to Merleau-Ponty.

Objectives: to describe the family's experience in relation to daily life with a family member experiencing mental suffering.

Methods: a qualitative, descriptive, phenomenological study grounded in Merleau-Ponty's ontology of experience was conducted in ten households in a city in the state of Bahia, Brazil, where 24 participants of the Intersubjectivity Wheels reside. The descriptions produced were subjected to the Ambiguity Analytics technique.

Characterization of the Toxigenic Potential of Isolated from Raw Berries and Their Products.

is estimated to be responsible for 1.4-12% of all food poisoning outbreaks worldwide. The objective of this study was to investigate the toxigenic potential of 181 isolates of previously recovered from different types of berries and berry products (strawberries, raspberries, blackberries, and blueberries) by assessing the presence of enterotoxin genes (, , , , , , and ) and an emetic toxin cereulide synthetase gene ().

The care provided to black-skinned children and adolescents with mental health problems in the intersection between gender and race.

Objective: to characterize the sociofamily profile of black-skinned children and adolescents with mental health problems and to intersectionally describe who assumes responsibility for their care.

Method: a descriptive and exploratory study with a quantitative approach, developed in the Psychosocial Care Center for Children and Adolescents from the North region of the municipality of São Paulo. The data were collected from 47 family members of black-skinned children and adolescents, using a script with predefined variables submitted to statistical analysis.

The ability of Psychosocial Care Centers specialized in Alcohol and Drugs to handle crises.

Objective: (1) To our knowledge, this is the first study to evaluate CAPS AD's ability to handle crises. (2) The ability to handle crises of the CAPS AD from downtown São Paulo was 86.6%.

Susceptibility and transcriptomic response to plasma-activated water of Listeria monocytogenes planktonic and sessile cells.

Plasma-Activated Water (PAW) was generated from tap water using a surface dielectric barrier discharge at different discharge power (26 and 36 W) and activation time (5 and 30 min). The inactivation of a three-strain Listeria monocytogenes cocktail in planktonic and biofilm state was evaluated. PAW generated at 36 W-30 min showed the lowest pH and the highest hydrogen peroxide, nitrates, nitrites contents and effectiveness against cells on planktonic state, resulting in 4.

Surveillance on ESBL- and Indicator ARG in Wastewater and Reclaimed Water of Four Regions of Spain: Impact of Different Disinfection Treatments.

In the present study, the occurrence of indicator antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) both in the influent and the effluent of four Spanish wastewater treatment plants (WWTPs) was monitored for 12 months, and the susceptibility profiles of 89 recovered extended spectrum β-lactamase (ESBL)-producing isolates were obtained against a wide range of antimicrobials. The aim of the study was to better understand whether the current wastewater treatment practices allow us to obtain safe reclaimed water mitigating the spread of ARB and ARGs to the environment. Results showed high concentrations of ESBL-producing as well as a high prevalence of a range of ARGs in the influent samples.

Caring for Adolescents and Young Adults With Tuberculosis or at Risk of Tuberculosis: Consensus Statement From an International Expert Panel.

Background:: Despite being a preventable and treatable disease, tuberculosis (TB) is a leading cause of death among young people globally. Each year, an estimated 1.8 million adolescents and young adults (AYAs; 10–24 years old) develop TB.

Cytotoxicity of Extracts from Leaves on Yeast.

L. is a plant used in traditional medicine harboring pharmacological properties with anti-inflammatory, antinociceptive, hypoglycemiant and anesthetic activities. This study assessed the potential cytotoxic, genotoxic and mutagenic effects of ethanolic extract of on strains.

The background microbiota and sanitization agent drive the fate of Listeria monocytogenes in multispecies biofilms formed on a plasma-polymerized coating applied on stainless steel.

The present study evaluates the anti-biofilm activity of a coating applied with an atmospheric-pressure plasma jet system on AISI 316 stainless steel (SS) against multispecies biofilms containing Listeria monocytogenes (using background microbiota from three different meat industries) using culture-dependent and culture-independent approaches. Also, the disinfection effectiveness and biofilm evolution after sanitization with two food industry biocides were assessed. The anti-biofilm activity of the coating against L.

SARS-CoV-2 in Brazil and Psychosocial Repercussions on Men's Health: Health Literacy Is Important.

This study aimed at analyzing the psychosocial repercussions of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic on the health of men living in Brazil. For this, we carried out a socio-historical and qualitative study, with the participation of 200 men who answered an online questionnaire. The data collected were processed in the NVIVO12® software, structured by the Collective Subject Discourse method, and analyzed from the epidemic disease theoretical framework proposed by Charles Rosenberg.