Publications by authors named "Marcia K Horn"

The increased use of telehealth in cancer care during the coronavirus disease 2019 pandemic has added to our knowledge and experience of the modality with benefits in terms of efficacy, cost, and patient and healthcare professional experience reported. However, telehealth has also been found not to be universally available to all patients with cancer, nor to be appropriate for every healthcare interaction; additionally, not all patients prefer it. Now that coronavirus disease restrictions have essentially ended and an opportunity to re-assess telehealth provision in cancer care presents, we offer a framework that aims to ensure that the needs and preferences of the patient community are included in the development of telehealth provision.

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Article Synopsis
  • - The study focuses on non-small cell lung cancers (NSCLCs), which commonly involve mutations, aiming to identify patient-reported outcome (PRO) measures for clinical trials that assess symptoms and quality of life.
  • - Thirty NSCLC patients from the U.S., Europe, and Asia participated in interviews and reported symptoms, with fatigue, shortness of breath, cough, and weight loss being the most common issues; those with exon 20 mutations faced more severe impacts on daily life but not necessarily on emotions.
  • - The PROMIS Short-Form version 2.0-Physical Function 8c and the NSCLC Symptom Assessment Questionnaire were found to be clear and relevant, suggesting they are suitable for future clinical studies involving
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Context: Patient-reported outcomes (PROs) are used in parallel with clinical evidence to inform decisions made by industry, clinicians, regulators, health technology assessment bodies and other health-care decision-makers. In addition, PRO data can also guide shared decision making and individual patient choice. Yet, the quality of many PROs in cancer clinical trials is suboptimal and requires improvement to add value to health care and policy decision making.

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