Effects of fish oil supplementation on spatial memory in rats with pilocarpine-induced epilepsy assessed using the Morris Water Maze test.

Objective: Patients with temporal lobe epilepsy (TLE) are at high risk of experiencing cognitive impairment. Such dysfunction is also observed in an animal model of TLE, the rat model of pilocarpine-induced epilepsy.

Methods: We investigated the effects of fish oil supplementation on spatial memory in rats with pilocarpine-induced epilepsy using the Morris Water Maze (MWM) test.

Assessment of vitamin D and inflammatory markers profile in cardiac tissue on Parkinson disease animal model.

Background: Cardiovascular dysfunctions are common non-motor symptoms in patients with Parkinson's disease (PD) that can result in reduced quality of life and even death. Research in animal models designed to characterize the pathological association between PD and cardiovascular abnormalities is still in its infancy. This study assessed the early impact of the nigrostriatal dopaminergic damage on cardiological features in the unilateral 6-OHDA rat model of PD.

Endogenous protection against the 6-OHDA model of Parkinson's disease in the Amazonian rodent Proechimys.

Background: Proechimys, an epilepsy-resistant rodent from Amazon Rainforest, is a promising alternative animal model for studying neurodegenerative disorders.

Objectives: To evaluate behavioral and immunohistological changes in Proechimys after 6-OHDA-induced model of PD.

Methods: Following unilateral injections of 6-OHDA into striatum, animals were assessed for exploratory behavior using the cylinder test.

Gold Nanoparticles for X-ray Microtomography of Neurons.

Commonly used methods to visualize the biological structure of brain tissues at subcellular resolution are confocal microscopy and two-photon microscopy. Both require slicing the sample into sections of a few tens of micrometers. The recent developments in X-ray microtomography enable three-dimensional imaging at sub-micrometer and isotropic resolution with larger biological samples.

Long-term Potentiation Decay and Poor Long-lasting Memory Process in the Wild Rodents from Brazil's Amazon Rainforest.

are small terrestrial rodents from Amazon rainforest. Each animal species is adapted to a specific environment in which the animal evolved therefore without comparative approaches unique characteristics of distinct species cannot be fully recognized. Laboratory rodents are exceedingly inbred strains dissociated from their native habitats and their fundamental ecological aspects are abstracted.