Association of TMAO levels with indicators of ulcerative colitis activity.

Background: The diagnosis of ulcerative colitis (UC) today is limited to a small number of biomarkers. Trimethylamine-N-oxide (TMAO) is the product of reactions resulting from the degradation of dietary-free choline, phosphatidylcholine, and carnitine metabolism by the intestinal microbiota. Earlier studies showed his involvement in the pathogenesis of UC.

Spontaneous switching and fine structure of donor-acceptor Stenhouse adducts on Au(111).

We present the spontaneous isomerization of donor-acceptor Stenhouse adducts anchored onto a gold surface, visualized using scanning tunneling spectroscopy. Our investigation reveals a palette of molecular arrangements, including those with ferroelectric-like ordering, evolving over time into a fine pattern consisting of both open and closed forms of the photoswitch.

New approach to the mitral valve through the left anterior minithoracotomy for combined valve and coronary surgical procedures.

Objective: We have developed a new technique for accessing the mitral valve through the left anterior minithoracotomy. This approach has been used in patients requiring both mitral valve surgery and coronary artery bypass grafting.

Methods: From October 2020 to September 2022, we performed 24 concomitant mitral valve procedures and coronary artery bypass grafting through the left anterior minithoracotomy.

Polar Self-Organization of Ferroelectric Nematic-Liquid-Crystal Molecules on Atomically Flat Au(111) Surface.

Understanding nanoscale mechanisms responsible for the recently discovered ferroelectric nematics can be helped by direct visualization of self-assembly of strongly polar molecules. Here, we report on scanning tunneling microscopy studies of monomolecular layers of a ferroelectric nematic liquid crystal on a reconstructed Au(111) surface. The monolayers are obtained by deposition from a solution at ambient conditions.

New approach for combined aortic valve and coronary procedures through the left anterior minithoracotomy.

Objectives: We have developed a novel technique for accessing the aortic valve (AoV) through the left anterior minithoracotomy (LAmT). This approach has been used in patients requiring both AoV surgery and coronary artery bypass grafting (CABG).

Methods: From April 2023 to July 2023, we performed 6 concomitant AoV procedures and CABG through the LAmT.

essential oil: GC-MS analysis, antibacterial activity and effect on the formation of biofilms.

essential oil (SDEO) was obtained using a Clevenger apparatus by hydrodistillation approach. The chemical composition of the essential oil was determined by GC-MS analysis. In this study SDEO was screened for its antibacterial activity against , , and and the amount of biofilm formed by bacteria.

Notes on the Taxonomy of (Salicaceae).

L., or golden willow, was described by C. Linnaeus in 1753.

Left anterior minithoracotomy as a first-choice approach for isolated coronary artery bypass grafting and selective combined procedures.

Objectives: Our goal was to describe the technique for and evaluate the results of the isolated coronary artery bypass grafting or combined grafting procedures with mitral valve repair/replacement and/or left ventricle aneurysm repair performed through a single left anterior minithoracotomy.

Methods: Perioperative data of all patients who required isolated or combined coronary grafting from July 2017 to December 2021 were observed. The focus was on 560 patients who underwent isolated or combined multivessel coronary bypass using the "Total Coronary Revascularization via left Anterior Thoracotomy" technique.

A dataset of direct observations of sea ice drift and waves in ice.

Variability in sea ice conditions, combined with strong couplings to the atmosphere and the ocean, lead to a broad range of complex sea ice dynamics. More in-situ measurements are needed to better identify the phenomena and mechanisms that govern sea ice growth, drift, and breakup. To this end, we have gathered a dataset of in-situ observations of sea ice drift and waves in ice.

HYPERPLASIA OF THE FEMALE REPRODUCTIVE ORGANS IN UKRAINE.

Objective: The aim: To determine the role of infectious diseases as the cause of the Cervical, Ovarian and Breast hyperplasia in Ukraine.

Patients And Methods: Materials and methods: We conducted a retrospective multicenter cohort study from January 1st, 2020 to December 31st, 2022. This study included patients aged 20-59 years with a diagnosis of hyperproliferative pathology of the women reproductive organs without atypia, who sought medical care for hyperplastic processes admitted to the 12 hospitals from 9 regions of Ukraine.

The Ovule Number Variation Provides New Insights into Taxa Delimitation in Willows ( subgen. ; Salicaceae).

, and are closely related species characterized by the lanceolate, acuminate and serrulate leaves. The boundaries between them are defined by relatively few diagnostic characters, and their identification is not fully solved. Recent studies have demonstrated that the number of ovules present in the ovaries of the willow flower can assist in the identification of the species.

Organometallic Synthesis of 2,3,6,7-Tetrasubstituted 1,8-Bis(dimethylamino)naphthalenes for Investigation of the Double Buttressing Effect in Proton Sponges.

The lithiation of 2,7-disubstituted derivatives of 1,8-bis(dimethylamino)naphthalene (DMAN, proton sponge) bearing potentially -directing OMe, NMe, and SMe groups was studied. It has been shown that OMe groups facilitate selective dual β-lithiation of the naphthalene moiety while the 2(7)-NMe groups allow only monolithiation presumably due to the decreased acidity of the ring C-H bonds and conformational immobilization after coordination to the lithium atom. In contrast, the SMe groups provided no ring lithiation and underwent deprotonation of their methyl fragment.

Surgical Maneuver for Ventricular Septal Defect Exposure During Congenital Heart Surgery Through the Right Axillary Transverse Minithoracotomy.

Right axillary transverse minithoracotomy is not conventionally used for ventricular septal defect (VSD) repair because of complicated VSD exposure and the need for a temporary tricuspid valve leaflet detachment to facilitate VSD exposure. Recently, our team developed a new, not previously described surgical maneuver that markedly facilitates perimembranous VSD exposure without any need for tricuspid valve leaflet detachment. The above-mentioned VSD exposure maneuver was used in 21 patients with a median age of 5 months (range, 1.

[Anatomical and morphometric features of anterior eye segment structures in hyperopia and the risk of developing primary angle-closure glaucoma].

Purpose: To study features of anatomical and morphometric parameters of the structures of anterior eye segment in young patients with moderate and high hyperopia in order to identify the signs of an increased risk of developing primary angle-closure glaucoma (PACG) and its acute attack.

Material And Methods: The study included 160 eyes (80 patients) with axial length (AL) of less than 23 mm. Patients with moderate or high hyperopia were divided into two groups according to their age ranges (the 1 - 27 patients (54 eyes) under 40 years old; the 2 - 27 patients (54 eyes) of 41-50 years old, the comparison group - 26 patients (52 eyes) of 42-50 years old with the initial stage of PACG.

IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma.

Unlabelled: Although inflammatory mechanisms driving hepatocellular carcinoma (HCC) have been proposed, the regulators of anticancer immunity in HCC remain poorly understood. We found that IL27 receptor (IL27R) signaling promotes HCC development in vivo. High IL27EBI3 cytokine or IL27RA expression correlated with poor prognosis for patients with HCC.

Surgical treatment of Kommerell's diverticulum.

Kommerell's diverticulum (KD) is a rare congenital vascular abnormality due to the formation of an abnormal aortic arch, most commonly associated with dilatation at the proximal part of the aberrant subclavian artery. This article describes an option of surgical treatment in a patient with KD. The proposed new technique of aortic arch surgical reconstruction with a stent-graft placement in the descending aorta reduces CPB time, aortic clamp and circulatory arrest time.

[Phacoemulsification in prevention of acute angle-closure glaucoma attack].

Unlabelled: Analysis of the effectiveness of preventative phacoemulsification (PE) in anatomically short eyes with an increased risk of an acute glaucoma attack in thickened lens can help in choosing the optimal management tactics for these patients.

Purpose: To study the changes in morphometric parameters of the anterior segment of anatomically short eyes with an increased risk of acute glaucoma attack before and after preventative PE.

Material And Methods: The study included 70 patients (70 eyes) with a high risk of acute glaucoma attack in short anatomical axial length and thickened lens, with posterior and middle positions of the ciliary body.

Dinuclear gold(I) complexes with -phosphanyl, N-heterocyclic carbene ligands: synthetic strategies, luminescence properties and anticancer activity.

A small library of dinuclear gold(I) complexes with the title ligands has been prepared, encompassing neutral, mono- and dicationic complexes. The luminescence properties of the complexes in the solid state have been evaluated, and it turns out that neutral and monocationic complexes not presenting a rigid metallamacrocyclic structure can exhibit rather strong emissions that extend towards the red region of the visible spectrum. The anticancer activity of the complexes has been also preliminarly evaluated; cytotoxicity seems to correlate with complex lipophilicity, whereas selectivity towards cancer cells can be apparently enhanced upon a judicious choice of the ligands.

EPIDEMIOLOGICAL DATA ON THE DETECTION OF IMMUNOGLOBULINS OF CLASS IGM, IGG TO SARS-COV-2 AMONG POPULATION OF POLTAVA REGION.

Objective: The aim: Of this study was to analyze epidemiological data on the detection of immunoglobulins of class M and G (IgM, IgG) to SARS-CoV-2 among urban and rural population of Poltava region.

Patients And Methods: Materials and methods: We have analyzed the research results of 2841 patients to determine IgM and IgG levels to SARS-CoV-2. The study included the results of patients in Poltava and nearby villages of Poltava region, obtained during July - December 2020.

Combination of "Buttressing" and "Clothespin" Effects for Reaching the Shortest NHN Hydrogen Bond in Proton Sponge Cations.

A series of previously unknown 2,4,5-tri- and 2,4,5,7-tetrasubstituted 1,8-bis(dimethylamino)naphthalenes and their salts with HBF containing bulky spherically shaped substituents (Me, Br, and SiMe) in the naphthalene ring has been synthesized. Using XRD analysis of 11 samples, the influence of the so-called "buttressing" and "clothespin" effects on their molecular structure and the NHN hydrogen bond geometry in the solid cations were investigated. The combined action of both effects has been shown to significantly increase the compression of the hydrogen bond.

Wolfe procedure in a 78-year-old patient with aortic root aneurysm: A case report.

Background: Aortic root and ascending aortic aneurysms are traditionally surgically treated through the deployment of a conduit with an artificial aortic valve, which significantly increases the risk of postoperative complications in the form of thrombosis.

Materials & Methods: We report a case of Wolfe procedure in a 78-year-old female patient with aortic root aneurysm at high risk for conventional Bentall surgery.

Discussion And Conclusion: We use this case to discuss the effectiveness and short-term results of this procedure.

Seasonal Dynamics of Testosterone and Corticosterone in Predatory Birds as Exemplified by the Northern Goshawk (Accipiter gentilis).

Testosterone and corticosterone are steroid hormones that regulate various aspects of bird behavior. The dynamics of blood level of these hormones depending on the stage of the life cycle have been studied in many species. It has been shown for both sexes that the levels of both hormones rise during the breeding season.