Publications by authors named "Marcelo de Azevedo E Souza Munhoz"
Viability of Collagen Matrix Grafts Associated with Nanohydroxyapatite and Elastin in Bone Repair in the Experimental Condition of Ovariectomy.
Int J Mol Sci
October 2023
Bone lesions have the capacity for regeneration under normal conditions of the bone metabolism process. However, due to the increasing incidence of major traumas and diseases that cause bone-mineral deficiency, such as osteoporosis, scaffolds are needed that can assist in the bone regeneration process. Currently, natural polymeric scaffolds and bioactive nanoparticles stand out.
View Article and Find Full Text PDFArticle Synopsis
- - The study focuses on post-traumatic osteoarthritis (PTOA), which affects about 12.4% of individuals, particularly looking at the injuries that lead to the most pain and disability in non-athletes, and how these injuries compare to primary osteoarthritis (OA) in terms of patient characteristics and complications post-surgery.
- - A cohort of 1,290 participants with joint issues was analyzed, revealing that PTOA patients were generally younger and had higher alcohol consumption and more significant comorbidities like osteoporosis and psychosis compared to those with primary OA.
- - Findings indicated that meniscal injuries and hip fractures were the most painful and disabling injuries related to PTOA, with knee fractures being more common in men
Role of central obesity on pain onset and its association with cardiovascular disease: a retrospective study of a hospital cohort of patients with osteoarthritis.
BMJ Open
December 2022
Objectives: To determine the role of central obesity (CO) in the onset and severity of joint pain and in predicting cardiovascular disease (CVD) in subjects affected with osteoarthritis (OA).
Design: Retrospective analysis on the onset of OA joint pain and CO. Waist circumference (WC), Waist-to-height ratio andwaist-to-hip ratio (WHR) were measured at the interview and defined according to the WHO criteria.
Article Synopsis
- Autologous bone grafts are the gold standard for treating extensive bone loss, but they have limitations related to donor area and complications, prompting the need for new biomaterials.
- The study tested the effects of elastin and collagen matrices on bone repair in rats with critical size defects, comparing a control group with two groups using different biomaterials.
- Results showed that both matrices significantly improved bone growth compared to the control group, with the porcine collagen matrix yielding the best outcomes.
Objective: (1) To investigate differences in pain severity and its distribution between patients with and without diabetes mellitus (DM) in a population with advanced osteoarthritis (OA). (2) To explore the role of medication used for diabetes in these associations.
Research Design And Methods: This is a hospital-based cohort study of patients with advanced OA requiring total joint arthroplasty.
Background: Total joint arthroplasty (TJA) benefit patients with osteoarthritis (OA) and rheumatoid arthritis (RA). However, a specific approach to detect patients at higher risk of prosthetic joint infection (PJI) and mechanical complications is absent. The aim of this study is to identify groups at higher risk for infections and mechanical complications after TJA in patients with RA and OA based on their most significant predictors.
View Article and Find Full Text PDFA simple method to minimize vascular lesion of the popliteal artery by guidewire during transtibial posterior cruciate ligament reconstruction: a cadaveric study.
Arthroscopy
September 2014
Purpose: To compare the outside-in transtibial lateral and medial approaches for posterior cruciate ligament (PCL) reconstruction regarding the guidewires and popliteal artery integrity.
Methods: Twenty-two human cadaveric knees were used. A PCL tibial aimer was arthroscopically placed within the PCL footprint through the anteromedial portal for the medial approach and through the anterolateral portal for the lateral approach.