[Ulcerative esophagitis associated with the use of alendronate sodium: histopathological and endoscopic features].

Background: Drug-induced or "pill-induced" esophagitis may be secondary to the prolonged contact of the drug with the esophageal mucosa or secondary to the drug ability to alter the local conditions. The alendronate sodium, a bone resorption inhibitor used in the treatment and prevention of osteoporosis, has been cited, recently, as one of the causes of adverse upper gastrointestinal tract injury.

Aim: To describe the clinical, endoscopic and histopathological features of patients with ulcerative esophagitis associated with alendronate sodium.