Expression of CD28, FAS, PD1, and CTLA4 molecules in the blood of women with triple-negative breast cancer.

Background: Locally advanced triple-negative breast cancer (TNBC) represents a public health problem in Brazil. Its standard treatment consists of neoadjuvant chemotherapy (NAC).

Methods: This was a longitudinal study with follow-up performed between the years 2015 and 2017.

Prognostic role of SOX2 and STAT3 expression on circulating T lymphocytes and CD44+/CD24 cells in the locally advanced and metastatic breast cancer.

Background: Breast cancer (BC) is associated with a continuous increase in incidence, with high mortality rates in several countries. CD44, STAT3, and SOX2 are related to regulating of somatic cell division, tumorigenesis, and metastasis in BC.

Methods: A cross-sectional study was carried out at the Hospital de Cancer de Pernambuco (HCP) between 2017 and 2018.