Mental health and weight regain after bariatric surgery: associations between weight regain and psychiatric and eating-related comorbidities.

Objective: Weight regain is a common outcome of weight loss interventions. Mental health-related comorbidities, among other factors, can mediate weight regain regardless of the implemented treatment modality. This study explores whether postoperative psychopathological comorbidities are associated with weight regain after bariatric surgery.

Binge Eating Disorder: A 5-Year Retrospective Study on Experimental Drugs.

Binge eating disorder (BED) affects a significant rate of the general population causing a negative impact on their quality of life, weight, and self-esteem. Besides psychological treatments that compose the majority of the studies, pharmaceuticals have contributed to improve a host of clinical parameters, thus being an important component of the treatment. We opted to target the latest results by performing a review of the literature on the pharmacology for BED from the last 5 years.

Does binge-eating matter for glycemic control in type 2 diabetes patients?

Background: Eating behavior is an important aspect related to type 2 diabetes mellitus (T2DM) treatment and may have an impact on glycemic control. Previous reports showed elevated prevalence of eating disordered behaviors, especially binge eating disorder in clinical samples of type 2 diabetes patients. However, results regarding the impact of an eating disorder on the glycemic and clinical control of T2DM is inconsistent.

Profile of agomelatine and its potential in the treatment of generalized anxiety disorder.

Background: Although many generalized anxiety disorder (GAD) patients respond to the available pharmacological treatments, nearly half of them do not present the expected results. Besides, the side effects associated to some drugs have a negative impact on treatment adherence. Therefore, the aim of this review was to report the clinical profile of agomelatine, a selective melatonergic MT1/MT2 receptor agonist with serotonin 5-HT2c receptor antagonist activities, as a potential pharmacological option in the treatment of GAD.

A review of preliminary observations on agomelatine in the treatment of anxiety disorders.

Agomelatine is an antidepressant with a novel mechanism of being a selective melatonergic MT₁/MT₂ receptor agonist with serotonin 5-HT(2c) receptor antagonist activities. Although the vast majority of the clinical data concerning the effectiveness of agomelatine concern its antidepressant properties, there is also preliminary evidence of anxiolytic effects. The purpose of the study was to perform a review of studies that investigated the efficacy of agomelatine in the treatment of anxiety disorders (ADs) and a discussion of the clinical utility of agomelatine in this clinical population.

Depression, glycemic control and type 2 diabetes.

Background: Comorbid depression in diabetes has been suggested as one of the possible causes of an inadequate glycemic control. The purpose of this study was to investigate the association between major depression and the glycemic control of type 2 diabetes mellitus (T2DM).

Methods: Seventy T2DM patients were evaluated.

Impact of body mass index on the psychopathological profile of obese women.

Objective: Obesity is a complex condition associated with a host of medical disorders. One common assumption is that obesity is also related to psychological and emotional complications. However, some studies have shown that obesity itself does not appear to be systematically associated with psychopathological outcomes.

Impact of binge eating disorder in the psychopathological profile of obese women.

Objective: Our objective was to evaluate the psychopathological profile of obese women with binge eating disorder (BED) using the Symptom Checklist-90 (SCL-90).

Methods: Two hundred twelve obese women who seek for weight loss treatment were sequentially selected to participate in the study. Binge eating disorder was diagnosed using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition.

[Translation into Portuguese and assessment of the reliability of a scale for the diagnosis of diabetic distal polyneuropathy].

The aim of this study was to translate into Portuguese and to assess the reliability of an instrument for the diagnosis of diabetic distal polyneuropathy (DPN). The process for translation and adaptation into Portuguese of the Neuropathy Symptom Score (NSS) and the Neuropathy Disability Score (NDS) was performed following internationally standardized procedures. The instruments were applied by 2 raters in 57 consecutive subjects.

Prevalence of eating disorders and psychiatric comorbidity in a clinical sample of type 2 diabetes mellitus patients.

Background: A few studies have shown high rates of eating disorders and psychiatric morbidity in patients with type 2 diabetes mellitus.

Objective: Disturbed eating behavior and psychiatric comorbidity in a sample of T2DM patients.

Methods: Seventy type 2 diabetes mellitus patients between 40 and 65 years of age (mean, 52.

Psychiatric comorbidity in a Brazilian sample of patients with binge-eating disorder.

We compared sociodemographic characteristics and psychiatric status in obese Brazilian patients who did (n=32) and did not (n=33) meet DSM-IV criteria for binge-eating disorder (BED). The sample's mean age was 35.0 years (+/-10.

Topiramate use in obese patients with binge eating disorder: an open study.

Objective: To assess topiramate's efficacy and tolerability in a group of obese binge eaters with no neuropsychiatric comorbidity.

Method: We consecutively selected 8 obese patients with binge eating disorder (BED) and no medical or psychiatric comorbidity from individuals seeking treatment for obesity. Treatment with topiramate at 150 mg daily was administered over a 16-week period.