Case reports of a new syndrome associating gingival fibromatosis and dental abnormalities in a consanguineous family.

Background: Gingival fibromatosis (GF) is characterized by fibrotic enlargement of the gingiva that can be inherited as an isolated trait (named hereditary gingival fibromatosis) or as a component of a syndrome. This article reports one kindred affected by a syndrome characterized by GF associated with dental abnormalities (DA) including generalized thin hypoplastic amelogenesis imperfecta (AI).

Methods: To characterize the pattern of inheritance and the clinical features, 70 family members were examined.