The Effect of Periodontal Diseases and Cognitive Deficit on Behavioral State, Oxidative Stress Parameters and Alveolar Bone Loss in Rats.

Aims: To evaluate the effect of periodontal disease (PD) and cognitive deficit (CD) on behavioral state, oxidative stress parameters, and alveolar bone loss (ABL).

Materials And Methods: Fifty male Wistar rats were randomly divided into five groups: control; scopolamine; periodontal disease (PD); PD+scopolamine evaluated by the Morris water maze behavioral test; PD+scopolamine assessed by the inhibitory avoidance behavioral test. PD and CD were, respectively, induced by ligature and scopolamine.