Publications by authors named "Marcelo Cerilo-Filho"
The coinfection between malaria (ML) and arboviral diseases represents a major global public health problem, particularly in tropical and subtropical countries. Despite its relevance, this topic is still insufficiently discussed in the current literature. Here, we aimed to investigate the worldwide distribution, symptoms, and diagnosis during coinfection between ML and arboviral diseases.
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- The study investigates the role of TREM-1 gene polymorphisms in the immune response to malaria, specifically in patients infected with Plasmodium vivax in the Brazilian Amazon.
- Researchers analyzed blood samples from 76 infected individuals and 144 healthy controls, measuring various cytokines and antibodies to understand their relationship with TREM-1 polymorphisms.
- Results showed significant associations between certain gene variants and increased levels of inflammatory cytokines in malaria patients, suggesting these SNPs could influence the severity of the disease.