Publications by authors named "Marcello Divino"
Article Synopsis
- Obstructive sleep apnoea (OSA) is prevalent among elderly patients with cardiovascular issues, yet it often goes unrecognized and untreated.
- The study enrolled 420 patients aged 65+ with paroxysmal atrial fibrillation and moderate to severe OSA to compare the effects of Continuous Positive Airway Pressure (CPAP) treatment against no treatment over an average of 22 months.
- Results showed that CPAP significantly reduced the risk of major cardiovascular events (MACE) and recurrence of atrial fibrillation in patients when combined with regular medical care.
Article Synopsis
- Atrial fibrillation (AF) in older patients is linked to cognitive decline and dementia, with ongoing debate about the benefits of anticoagulants on cognitive function.
- This study involved 983 older patients comparing the cognitive decline between those on non-vitamin K oral anticoagulants (NOACs) and vitamin K antagonists (VKAs) using the Mini Mental State Examination (MMSE) score over an average of 7.2 years.
- Results showed that patients on NOACs had a significantly lesser decline in cognitive function compared to VKAs, indicating that NOACs may be more beneficial for preserving cognitive health in older AF patients despite their higher age and comorbidities.
Background: Heart failure (HF) with preserved ejection fraction (HFpEF) represents a major comorbidity in the elderly and is associated with cognitive impairment (CoI) and type 2 diabetes mellitus (T2DM). In this context, there is an increase in oxidative stress and platelet activation biomarkers. The aim of this study was to evaluate the effects of 6 months' treatment with SGLT2i on functional, mood-related, and cognitive aspects, assessed by performing a comprehensive geriatric assessment (CGA), and on oxidative stress and platelet activation biomarkers, in a cohort of HFpEF elderly patients with T2DM.
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