Search for Strange Quark Matter and Nuclearites on Board the International Space Station (SQM-ISS): A Future Detector to Search for Massive, Non-Relativistic Objects in Space.

SQM-ISS is a detector that will search from the International Space Station for massive particles possibly present among the cosmic rays. Among them, we mention strange quark matter, Q-Balls, lumps of fermionic exotic compact stars, Primordial Black Holes, mirror matter, Fermi balls, etc. These compact, dense objects would be much heavier than normal nuclei, have velocities of galaxy-bound systems, and would be deeply penetrating.

Infrared Spectroscopy of SARS-CoV-2 Viral Protein: from Receptor Binding Domain to Spike Protein.

Spike (S) glycoprotein is the largest structural protein of SARS-CoV-2 virus and the main one involved in anchoring of the host receptor ACE2 through the receptor binding domain (RBD). S protein secondary structure is of great interest for shedding light on various aspects, from functionality to pathogenesis, finally to spectral fingerprint for the design of optical biosensors. In this paper, the secondary structure of SARS-CoV-2 S protein and its constituting components, namely RBD, S1 and S2 regions, are investigated at serological pH by measuring their amide I infrared absorption bands through Attenuated Total Reflection Infrared (ATR-IR) spectroscopy.

Per-Pixel Forest Attribute Mapping and Error Estimation: The Google Earth Engine and R Tool.

Remote sensing products are typically assessed using a single accuracy estimate for the entire map, despite significant variations in accuracy across different map areas or classes. Estimating per-pixel uncertainty is a major challenge for enhancing the usability and potential of remote sensing products. This paper introduces the open access tool, a novel statistical design-based approach that specifically addresses this issue by estimating per-pixel uncertainty through a bootstrap resampling procedure.

Characterization of CuAg Alloys with Low Ag Concentrations.

Copper-based alloys designed to combine high electronic and thermal conductivities with high mechanical strength find a wide range of applications in different fields. Among the principal representatives, strongly diluted CuAg alloys are of particular interest as innovative materials for the realization of accelerating structures when the use of high-gradient fields requires increasingly high mechanical and thermal performances to overcome the limitations induced by breakdown phenomena. This work reports the production and optical characterization of CuAg crystals at low Ag concentrations, from 0.

The onset of motor learning impairments in Parkinson's disease: a computational investigation.

The basal ganglia (BG) is part of a basic feedback circuit regulating cortical function, such as voluntary movements control, via their influence on thalamocortical projections. BG disorders, namely Parkinson's disease (PD), characterized by the loss of neurons in the substantia nigra, involve the progressive loss of motor functions. At the present, PD is incurable.

The ReadFree tool for the identification of poor readers: a validation study based on a machine learning approach in monolingual and minority-language children.

In this study, we validated the "ReadFree tool", a computerised battery of 12 visual and auditory tasks developed to identify poor readers also in minority-language children (MLC). We tested the task-specific discriminant power on 142 Italian-monolingual participants (8-13 years old) divided into monolingual poor readers (N = 37) and good readers (N = 105) according to standardised Italian reading tests. The performances at the discriminant tasks of the "ReadFree tool" were entered into a classification and regression tree (CART) model to identify monolingual poor and good readers.

Secondary Structures of MERS-CoV, SARS-CoV, and SARS-CoV-2 Spike Proteins Revealed by Infrared Vibrational Spectroscopy.

All coronaviruses are characterized by spike glycoproteins whose S1 subunits contain the receptor binding domain (RBD). The RBD anchors the virus to the host cellular membrane to regulate the virus transmissibility and infectious process. Although the protein/receptor interaction mainly depends on the spike's conformation, particularly on its S1 unit, their secondary structures are poorly known.

Observation vs. interaction in the recognition of human-like movements.

A crucial aspect in human-robot collaboration is the robot acceptance by human co-workers. Based on previous experiences of interaction with their fellow beings, humans are able to recognize natural movements of their companions and associate them with the concepts of trust and acceptance. Throughout this process, the judgment is influenced by several percepts, first of all the visual similarity to the companion, which triggers a process of self-identification.

Photon-shot-noise-limited transient absorption soft X-ray spectroscopy at the European XFEL.

Femtosecond transient soft X-ray absorption spectroscopy (XAS) is a very promising technique that can be employed at X-ray free-electron lasers (FELs) to investigate out-of-equilibrium dynamics for material and energy research. Here, a dedicated setup for soft X-rays available at the Spectroscopy and Coherent Scattering (SCS) instrument at the European X-ray Free-Electron Laser (European XFEL) is presented. It consists of a beam-splitting off-axis zone plate (BOZ) used in transmission to create three copies of the incoming beam, which are used to measure the transmitted intensity through the excited and unexcited sample, as well as to monitor the incoming intensity.

A new approach to deposit homogeneous samples of asbestos fibres for toxicological tests .

In this paper we describe the results obtained with a novel method to prepare depositions of asbestos fibres for toxicological tests . The technique is based on a micro-dispenser, working as an inkjet printer, able to deposit micro-sized droplets from a suspension of fibres in a liquid medium; we used here a highly evaporating liquid (ethanol) to reduce the experimental time, however other solvents could be used. Both the amount and spatial distribution of fibres on the substrate can be controlled by adjusting the parameters of the micro-dispenser such as deposition area, deposition time, uniformity and volume of the deposited liquid.

Maturation of Aluminium Adsorbed Antigens Contributes to the Creation of Homogeneous Vaccine Formulations.

Although aluminium-based vaccines have been used for almost over a century, their mechanism of action remains unclear. It is established that antigen adsorption to the adjuvant facilitates delivery of the antigen to immune cells at the injection site. To further increase our understanding of aluminium-based vaccines, it is important to gain additional insights on the interactions between the aluminium and antigens, including antigen distribution over the adjuvant particles.

End-to-End Transcript Alignment of 17th Century Manuscripts: The Case of .

The growth of digital libraries has yielded a large number of handwritten historical documents in the form of images, often accompanied by a digital transcription of the content. The ability to track the position of the words of the digital transcription in the images can be important both for the study of the document by humanities scholars and for further automatic processing. We propose a learning-free method for automatically aligning the transcription to the document image.

Sars-Cov2 world pandemic recurrent waves controlled by variants evolution and vaccination campaign.

While understanding the time evolution of Covid-19 pandemic is needed to plan economics and tune sanitary policies, a quantitative information of the recurrent epidemic waves is elusive. This work describes a statistical physics study of the subsequent waves in the epidemic spreading of Covid-19 and disclose the frequency components of the epidemic waves pattern over two years in United States, United Kingdom and Japan. These countries have been taken as representative cases of different containment policies such as "Mitigation" (USA and UK) and "Zero Covid" (Japan) policies.

Terahertz continuous wave spectroscopy: a portable advanced method for atmospheric gas sensing.

Motivated by the increasing demand to monitor the air-quality, our study proved the feasibility of a new compact and portable experimental approach based on Terahertz (THz) continuous wave high resolution spectroscopy, to detect the presence of the air's contaminants as greenhouse gases (GHG) and volatile organic compounds (VOCs). In this specific work, we first characterized, determining their molar absorption coefficient in the spectral region (0.06-1.

High Sensitivity Monitoring of VOCs in Air through FTIR Spectroscopy Using a Multipass Gas Cell Setup.

Human exposure to Volatile Organic Compounds (VOCs) and their presence in indoor and working environments is recognized as a serious health risk, causing impairments of varying severities. Different detecting systems able to monitor VOCs are available in the market; however, they have significant limitations for both sensitivity and chemical discrimination capability. During the last years we studied systematically the use of Fourier Transform Infrared (FTIR) spectroscopy as an alternative, powerful tool for quantifying VOCs in air.

Rapid Automatized Naming as a Universal Marker of Developmental Dyslexia in Italian Monolingual and Minority-Language Children.

Rapid Automatized Naming (RAN) is considered a universal marker of developmental dyslexia (DD) and could also be helpful to identify a reading deficit in minority-language children (MLC), in which it may be hard to disentangle whether the reading difficulties are due to a learning disorder or a lower proficiency in the language of instruction. We tested reading and rapid naming skills in monolingual Good Readers (mGR), monolingual Poor Readers (mPR), and MLC, by using our new version of RAN, the RAN-Shapes, in 127 primary school students (from 3rd to 5th grade). In line with previous research, MLC showed, on average, lower reading performances as compared to mGR.

Synchrotron radiation transmission by two coupled flat microchannel plates: new opportunities to control the focal spot characteristics.

An improved theoretical model to calculate the focal spot properties of coherent synchrotron radiation (SR) soft X-ray beams by combining and aligning two microchannel plates (MCPs) is presented. The diffraction patterns of the radiation behind the MCP system are simulated in the framework of the electrodynamical model of the radiation emission from two-dimensional finite antenna arrays. Simulations show that this particular optical device focuses the soft X-ray radiation in a circular central spot with a radius of ∼4 µm.

Insight into atmospheric deposition and spatial distribution of bioavailable iron in the glaciers of northeastern Tibetan Plateau.

Iron (Fe) is an essential micronutrient in glacial ecosystems and modulates global biogeochemical cycles. To find out the deposition concentration, multiple origins and release form of iron in various glacier areas of central Asia, this study investigated the total Fe (TFe) and dissolved-Fe (dFe, diameter < 0.45 or <0.

A multi-purpose high-pressure and high temperature gas-flow cell for operando optical Raman spectroscopy.

A multi-purpose in operando optical cell with temperature and gas pressure control is described. This device allows for in operando Raman spectroscopy measurements for different applications. Its original design includes a temperature control from room temperature up to 1000°C and a heating stage that provides uniform and stable thermal conditions.

Morphological, electronic, and magnetic properties of multicomponent cobalt oxide nanoparticles synthesized by high temperature arc plasma.

Many technological applications demand large amount of nanoparticles with well-defined properties, which is feasible only by using large-scale production methods. In this framework, we have performed structural and local geometric investigations of cobalt oxide nanoparticles synthesized by high temperature arc plasma route in helium and in air atmosphere with different arc currents, a competitive and low cost technological approach to synthesize large quantity of different types of nanoparticles. The complex scenario of phase fraction, shape, size distribution and hysteresis loop features of high temperature arc plasma synthesis of nanoparticles can be determined by the arc current and the selected gas.

A Model for Evaluating the Performance of a Multiple Keywords Spotting System for the Transcription of Historical Handwritten Documents.

This paper proposes a performance model for estimating the user time needed to transcribe small collections of handwritten documents using a keyword spotting system (KWS) that provides a number of possible transcriptions for each word image. The model assumes that only information obtained from a small training set is available, and establishes the constraints on the performance measures to achieve a reduction of the time for transcribing the content with respect to the time required by human experts. The model is complemented with a procedure for computing the parameters of the model and eventually estimating the improvement of the time to achieve a complete and error-free transcription of the documents.

One Step Is Not Enough: A Multi-Step Procedure for Building the Training Set of a Query by String Keyword Spotting System to Assist the Transcription of Historical Document.

Digital libraries offer access to a large number of handwritten historical documents. These documents are available as raw images and therefore their content is not searchable. A fully manual transcription is time-consuming and expensive while a fully automatic transcription is cheaper but not comparable in terms of accuracy.

Real-time quantitative detection of styrene in atmosphere in presence of other volatile-organic compounds using a portable device.

Exposure to styrene is a major safety concern in the fibreglass processing industry. This compound is classified by the International Agency for Research on Cancer as a possible human carcinogen. Several types of analytical equipment exist for detecting volatile organic compounds (VOCs) in the atmosphere; however, most of them operate ex-situ or do not provide easy discrimination between different molecules.

Metastable states in plateaus and multi-wave epidemic dynamics of Covid-19 spreading in Italy.

The control of Covid 19 epidemics by public health policy in Italy during the first and the second epidemic waves has been driven by using reproductive number R(t) to identify the supercritical (percolative), the subcritical (arrested), separated by the critical regime. Here we show that to quantify the Covid-19 spreading rate with containment measures there is a need of a 3D expanded parameter space phase diagram built by the combination of R(t) and doubling time T(t). In this space we identify the Covid-19 dynamics in Italy and its administrative Regions.

Epidemic spreading in an expanded parameter space: the supercritical scaling laws and subcritical metastable phases.

While the mathematical laws of uncontrolled epidemic spreading are well known, the statistical physics of coronavirus epidemics with containment measures is currently lacking. The modelling of available data of the first wave of the Covid-19 pandemic in 2020 over 230 days, in different countries representative of different containment policies is relevant to quantify the efficiency of these policies to face the containment of any successive wave. At this aim we have built a 3D phase diagram tracking the simultaneous evolution and the interplay of the doubling time,, and the reproductive number,measured using the methodological definition used by the Robert Koch Institute.