Publications by authors named "Marcela Janka-Zires"

Uric acid stones account for approximately 10 % of renal stone disease. These are the only crystals that can be managed with an oral treatment called chemolysis. Chemolysis also known chemolitholysis was first described in the late 60's, but was accepted as a medical treatment for uric acid stone disease in mid 80's.

View Article and Find Full Text PDF

Objective: HbA1C is the "gold standard" parameter to evaluate glycemic control in diabetes; however, its correlation with mean glucose is not always perfect. The objective of this study was to correlate continuous glucose monitoring (CGM)-derived hemoglobin glycation index (HGI) with microvascular complications.

Methods: We conducted a cross-sectional study including permanent users of CGM with type 1 diabetes mellitus or latent autoimmune diabetes of the adult.

View Article and Find Full Text PDF
Article Synopsis
  • - The study explores the connection between insulin resistance, measured via estimated glucose disposal rate (eGDR), and chronic complications in individuals with type 1 diabetes (T1D), indicating that insulin resistance plays a significant role in these complications.
  • - Researchers analyzed data from 70 T1D patients, finding that 30% had metabolic syndrome (MS), with those having MS showing lower eGDR levels compared to those without.
  • - The results demonstrated that eGDR effectively distinguishes between patients with and without diabetic complications such as nephropathy, retinopathy, and neuropathy, suggesting its potential for use in routine diabetes care despite the need for more diverse studies.
View Article and Find Full Text PDF

Objective: To examine the performance and agreement of 5 modalities for testing sensory neuropathy against a neurothesiometer among Hispanic patients with type 1 diabetes (T1D) in an outpatient setting.

Methods: A cross-sectional study was conducted at a tertiary reference center in Mexico City. Sensitivity, specificity, predictive values, and likelihood ratios were calculated using a VibraTip device, 128 Hz tuning fork, and the Semmes-Weinstein 5.

View Article and Find Full Text PDF

Only 30 percent of chronic diabetic foot ulcers heal after 20 weeks of standard treatment. Pirfenidone is a drug with biological, anti-inflammatory, and antifibrotic effects. The aim of this study was to evaluate the effect of topical pirfenidone added to conventional treatment in noninfected chronic diabetic foot ulcers.

View Article and Find Full Text PDF

Background: The development of metabolic syndrome has been described in patients with type 1 diabetes mellitus as the disease progresses over time. The purpose of this study is to assess the relationship between metabolic syndrome, albuminuria, and glomerular filtration rate, as well as to determine the prevalence of metabolic syndrome, in a group of Mexican patients with type 1 diabetes mellitus.

Methods: We conducted a cross-sectional study that included patients with type 1 diabetes mellitus who were diagnosed over 10 years ago and who are seen at the Diabetes Intensive Control Clinic of the Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran in Mexico City.

View Article and Find Full Text PDF

Background: Hypercalcemia is a rare but well recognized cause of acute and chronic pancreatitis. Hypercalcemia-related pancreatitis is mainly caused by primary hyperparathyroidism. The prevalence of pancreatitis in hyperparathyroidism varies worldwide and additional disease-modifying factors may play a role in its development.

View Article and Find Full Text PDF

Dermatomyositis is a connective tissue inflammatory disease characterized by muscle and skin inflammation. The dermatological manifestations that characterize the disease include heliotrope erythema, Gottron's papules, violaceous scalling patches, periungual erythema telangiectasias, poikiloderma and scaly red scalp. The diagnostic workup includes skin diagnosis, muscle biopsy, muscle enzymes, electromyography, ANAs, antibodies against SSA (Ro), SSB (La), Sm, nRNP, Jo-1 and PM-1.

View Article and Find Full Text PDF