Publications by authors named "Marcela E Nunez-Martinez"

Objectives: Bacterial infections are important causes of death. Some reports have shown that the COVID-19 pandemic may have had an impact on drug resistance. The objective of this work was to compare the resistance profiles between 2019 and 2020 in the emergency department, non-intensive care units (ICU), and ICU areas in Mexican hospitals.

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Background And Aim: Here, we assess the effect of adjuvant antioxidant therapies in septic shock patients with organ dysfunction and their effect on the enzymatic and non-enzymatic antioxidant systems.

Methods: Randomized clinical trial run between 2018 and 2022. One hundred and thirty-one patients with septic shock were included in five groups with 25, 27, 24, 26 and 29 patients each.

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Omicron is the most mutated SARS-CoV-2 variant-a factor that can affect transmissibility, disease severity, and immune evasiveness. Its genomic surveillance is important in cities with millions of inhabitants and an economic center, such as Mexico City. Results.

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Article Synopsis
  • The MTHFR enzyme influences homocysteine levels, and genetic variants (polymorphisms) in its gene can alter its activity, potentially increasing the risk for thromboembolic diseases.
  • A study examined how the C677T and A1298C polymorphisms in the MTHFR gene relate to homocysteine levels and prothrombotic markers in patients with pulmonary embolism (PE) and acute myocardial ischemia (AMI).
  • Analyzing 334 patient records revealed that specific genotypes were significantly more common in those with thrombotic conditions, with elevated homocysteine levels associated with certain genetic alleles linked to increased risk of AMI and severe PE events.
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