Diagnose of soil fertility properties of a representative agricultural mesoregion in the Cerrado biome as affected by land use.

In Brazil, most of cereal production is concentrated in the Cerrado which is characterized by poor soils. Thus, the soil fertility management is important for suitable use of Cerrado's soils. After 40 years of increasing use of Cerrado for agricultural purposes, this work aimed to evaluate the soil fertility of a representative area known as Triângulo Mineiro and Alto Paranaíba (TMAP) mesoregion.

Impact of telenutrition protocols in a web-based nutrition counseling program on adult dietary practices: Randomized controlled pilto study.

Objective: To analyze the effectiveness of two different telenutrition protocols on the dietary practices of adults.

Methods: This was a 12-week, randomized controlled trial, involving the application of different telenutrition protocols with online nutritional counseling. Two protocols were used, the multicomponent (MT), composed of multiple strategies combined, synchronously and asynchronously, and the traditional (TD), with only one synchronous strategy, in addition to the control group (CT).

Effects of natural products-based dentifrices on acrylic resin for denture bases: A simulated period of 4 years.

Purpose: To evaluate the antimicrobial activity of dentifrices based on Malva sylvestris and propolis and the effect on the acrylic resin.

Methods: The inhibitory effect against Candida albicans, Enterococcus faecalis and Streptococcus mutans was determined. The specimens of resin were divided into groups: Control (brushing with distilled water); brushing with Colgate; brushing with Protex; brushing with Malvatricin, brushing with Proporalcare Dental Gel and brushing with Green Propolis Dental Gel.

Scintigraphic and Echocardiographic Study of Patients with Pathogenic or Probably Pathogenic Variants of the TTR Gene without Overt Cardiac Involvement.

Background: Transthyretin amyloidosis (ATTR) is an infiltrative disease caused by abnormal protein deposition mainly in the heart and peripheral nervous system. When it affects the heart, the disease presents as restrictive cardiomyopathy; when it affects the peripheral and autonomic nervous system, it manifests as polyneuropathy, and is called familial amyloid polyneuropathy (FAP). There are two ATTR subtypes: wild-type ATTR, where there is no mutation, and mutant ATTR (ATTRm), which is characterized by a mutation in the gene encoding the transthyretin protein (TTR).

Long-term reduced functional capacity and quality of life in hospitalized COVID-19 patients.

Background: Persistent symptoms and exercise intolerance have been reported after COVID-19, even months after the acute disease. Although, the long-term impact on exercise capacity and health-related quality of life (HRQoL) is still unclear.

Research Question: To assess the long-term functional capacity and HRQoL in patients hospitalized due to COVID-19.

MicroRNA as potential biomarker for severity, progression, and therapeutic monitoring in animal models of limb-girdle muscular dystrophy: a systematic review.

Limb-girdle muscular dystrophies (LGMD) constitute a heterogeneous group of neuromuscular disorders in which there are alterations in proteins responsible for the preservation of muscle architecture and function, leading to proximal and progressive muscle weakness. There is, however, significant phenotypic and genotypic variation, as well as difficulty in establishing biomarkers that help to define pathogenic mechanisms and assess disease severity and progression. In this field, there is special attention to microRNAs, small non-coding RNA molecules related to the regulation of gene expression and, consequently, the production of proteins.

Antimicrobial resistance and epidemic clustering of late-onset neonatal infections in a Brazilian intensive care unit.

Nosocomial infections in the neonatal intensive care unit (NICU) tend to cluster and multidrug-resistant (MDR) pathogens are rising in developing countries. We did a retrospective cohort study of neonates admitted to a NICU in Brazil with late-onset neonatal sepsis (LOS) confirmed by blood culture from October 2012 to December 2016 and from July 2018 to December 2021. We defined a cluster of infection when at least two cases of LOS occurred within two different time intervals: 15 and 30 days with the same pathogen in different patients.

Towards direct and eco-friendly analysis of plants using portable X-ray fluorescence spectrometry: A methodological approach.

The assessment of the nutritional status of plants is traditionally performed by wet-digestion methods using oven-dried and ground samples. This process requires sampling, takes time, and it is non-environmentally friendly. Agricultural and environmental science have been greatly benefited by in-field, ecofriendly methods, and real-time element measurements.

Identifying the research, advocacy, policy and implementation needs for the prevention and management of respiratory syncytial virus lower respiratory tract infection in low- and middle-income countries.

Introduction: The high burden of respiratory syncytial virus (RSV) infection in young children disproportionately occurs in low- and middle-income countries (LMICs). The PROUD (Preventing RespiratOry syncytial virUs in unDerdeveloped countries) Taskforce of 24 RSV worldwide experts assessed key needs for RSV prevention in LMICs, including vaccine and newer preventive measures.

Methods: A global, survey-based study was undertaken in 2021.

The Galactagogue Effect of Maternal Ingestion of Corn-Based Preparations: A Preliminary Study.

Low human milk production frequently occurs in mothers of premature children with low birth weights who require intensive care. To investigate whether corn-based preparations increase human milk production in women with insufficient milk volumes. This was an intervention study evaluated whether there was an increase in human milk production after a mother's consumption of corn-based preparations.

The impact of bariatric and metabolic surgery on the morbidity and mortality of patients infected during the COVID-19 pandemic: a retrospective cohort study.

Background: Since the impact of the coronavirus disease 2019 (COVID-19) pandemic in March 2020, several studies have shown a strong relationship between obesity and severe cases of COVID-19. It is imperative to assess whether bariatric surgery exerts a protective effect in such cases.

Objective: This study aimed to assess the impact of bariatric surgery on the morbidity and mortality in obese patients during the COVID-19 pandemic.

Impact of rhinovirus on hospitalization during the COVID-19 pandemic: A prospective cohort study.

Background: Although the clinical course of the COVID-19 in adults has been extensively described, the impact of the co-detection of SARS-CoV-2 and rhinovirus on severity outcomes is not understood.

Objectives: This study aimed to compare the risk of hospitalization of outpatients with COVID-19 with and without the co-detection of rhinovirus in southern Brazil. Secondarily, such risk was also compared between all individuals with COVID-19 and those with single rhinovirus infection.

Comparison of Climacteric Symptoms, Quality of Life, and Self-Care Attitudes before and during the COVID-19 Pandemic.

Objectives: This study aimed to compare the climacteric symptoms, quality of life indices, and self-care attitudes in women before and during the coronavirus disease 2019 (COVID-19) pandemic.

Methods: This cross-sectional study was conducted between January 2020 and September 2021. The sample consisted of 342 climacteric women who were divided into two groups: before the pandemic (BP group; n = 62) and during the pandemic (DP group; n = 280).

Biochar mitigates bioavailability and environmental risks of arsenic in gold mining tailings from the eastern Amazon.

Artisanal gold mining has generated tailings highly contaminated by arsenic (As) in Cachoeira do Piriá, eastern Amazon, leading to severe risks to the environment. Such risks should be mitigated considering the bioavailable concentration of the element, since it implies immediate damage to the ecosystem. The objective of this study was to evaluate the potential of biochars in mitigating the environmental risks of bioavailable As concentrations in gold mining tailings from underground and cyanidation exploration.

Cognitive restraint, emotional eating and uncontrolled eating: Exploring factors associated with the cycle of behaviors during the COVID-19 pandemic.

The objective of this study was to analyze the factors associated with Cognitive Restraint, Emotional Eating, and Uncontrolled Eating behaviors with perceptions of life habits, body image, eating habits, and food consumption during the COVID-19 pandemic. Sociodemographic data, eating behavior, perceptions about life and eating habits, body image, and food consumption were collected. Factors associated with each of the three eating behaviors were accessed through three multiple linear regressions controlled for age, sex, BMI, education level, and monthly income.

Active Vegetarians Show Better Lower Limb Strength and Power than Active Omnivores.

Vegetarian diets have become popular among athletes and active individuals and can have advantages for physical performance, but the results are still conflicting regarding muscle strength and power. The aim of this study was to evaluate the diet and physical performance of vegetarians through tests of dynamic, isometric, and relative strength; muscle power; and aerobic capacity. In this cross-sectional study, 32 vegetarians and 26 omnivores, who were physically active, were evaluated for the Healthy Eating Index and performance tested back squat, handgrip strength, isometric deadlift strength, jump with countermovement, and maximum aerobic speed (MAS).

Pediatric COVID-19 patients in South Brazil show abundant viral mRNA and strong specific anti-viral responses.

COVID-19 manifests as a milder disease in children than adults, but the underlying mechanisms are not fully characterized. Here we assess the difference in cellular or humoral immune responses of pediatric and adult COVID-19 patients to see if these factors contribute to the severity dichotomy. Children's non-specific immune profile is dominated by naive lymphocytes and HLA-DRCX3CR1 dendritic cells; meanwhile, children show strong specific antibody and T cell responses for viral structural proteins, with their T cell responses differing from adults by having weaker CD8TNF T cells responses to S peptide pool but stronger responses to N and M peptide pools.

Multisystem inflammatory syndrome in children: a cross-sectional study of cases and factors associated with deaths during the COVID-19 pandemic in Brazil, 2020.

Objective: To characterize the clinical-epidemiological profile of multisystem inflammatory syndrome in children temporally associated with COVID-19 (MIS-C), and to identify factors associated with MIS-C deaths in Brazil, 2020.

Methods: This was a cross-sectional study, using national MIS-C monitoring data. Logistical regression was performed to estimate crude and adjusted odds ratios (OR).

Non-tuberculous cutaneous mycobacterioses.

Non-tuberculous mycobacteriosis, previously known as atypical, anonymous, opportunistic, or unclassified mycobacteriosis, refers to pathogenic mycobacterioses other than those caused by Mycobacterium tuberculosis and Mycobacterium leprae. These mycobacteria are known for their environmental distribution, mainly in water and soil. The incidence of non-tuberculous mycobacteriosis has been increasing in all countries and skin infections are being increasingly studied, mainly with the increase in immunosuppressive conditions and the development of new medications that affect immunological function.

Differential expression profiles of miRNAs and their putative targets in Schistosoma mansoni during its life cycle.

Background: Schistosomiasis is a disease caused by Schistosoma. Due to its complex life cycle, evolutionary position and sexual dimorphism, schistosomes have several mechanisms of gene regulation. MicroRNAs (miRNAs) are short endogenous RNAs that regulate gene expression at the post-transcriptional level by targeting mRNA transcripts.

Nifuroxazide as JAK2 inhibitor: A binding mode proposal and Hel cell proliferation assay.

Nifuroxazide has been employed as an anti-diarrheic agent since 1966, but in the last decade has brought to the research spotlight again due to its recently described antitumoral activity through the JAK2 inhibitory potential. Since 2008, more than 70 papers have been published about the issue and more are expected to the following years. Herein we discuss the findings of molecular modelling studies which were performed to elucidate the potential binding mode of this drug into the JAK2 ATP recognition site and also into the allosteric region near the catalytic site.

Effects of Different Forms of Denture Adhesives on Biofilm Formation, Adhesive Strength and Hygiene of Complete Dentures.

Purpose: To evaluate the effect of different forms of denture adhesives on the formation of biofilm and on adhesive strength, as well as the effectiveness of hygiene protocols for their removal.

Materials And Methods: Samples of the heat-cured polymethyl methacrylate denture base resin were made and divided into four groups: control (no adhesive), ultra Corega cream, Corega strip adhesive, and ultra Corega powder (GlaxoSmithKline). Biofilm formation was evaluated by counting colony-forming units and fluorescence microscopy.