Publications by authors named "Marcela C Salazar"
Biopolymers: Histopathologic Case Series of Patients with Permanent Synthetic Fillers Presenting Chronic Granulomatous Reaction and Hypercalcemia.
Plast Reconstr Surg Glob Open
October 2024
Article Synopsis
- Biopolymers are synthetic materials used as fillers but are not compatible with the body, potentially leading to adverse reactions and conditions known as foreign-body-induced human adjuvant disease.
- A study conducted in Bogotá, Colombia, involved 20 patients who had biopolymer removal surgeries, revealing significant inflammatory responses and signs that could complicate diagnosis, like cytoplasmic vacuolization in reactive adipocytes.
- It is advised that surgeons measure certain blood markers (lactate dehydrogenase, serum calcium, and parathyroid hormone) to evaluate complications, and that removing biopolymers surgically may help prevent further issues.
Classification for Staging and Managing Patients with Biopolymer-induced Human Adjuvant Disease.
Plast Reconstr Surg Glob Open
February 2022
Unlabelled: Biopolymer-induced human adjuvant disease (BHAD) is a chronic clinical condition that requires surgical intervention, regardless of the presence of symptoms, to minimize the risk of functional, aesthetic, and systemic sequelae and the development of conditions simulating autoimmune disease. We propose a classification for BHAD on the basis of course of the disease, which will make it possible to assess the damage and difficulty in patients, leading to a more appropriate therapeutic approach.
Methods: A protocol study was implemented.
Unlabelled: Biopolymers consist of non-biocompatible allogeneic materials. They have been associated with autoimmune inflammatory syndrome induced by adjuvants, as described by Yehuda Shoenfeld and Nancy Agmon-Levin. Therefore, this study aimed to evaluate the clinical and immunological characteristics of patients with autoimmune inflammatory syndrome induced by adjuvants treated at a plastic surgery clinic in Colombia.
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