Publications by authors named "Marcela Barguil"
Context: Although genetic influences on bipolar disorder are well established, localization of genes that predispose to the illness has proven difficult. Given that genes predisposing to bipolar disorder may be transmitted without expression of the categorical clinical phenotype, a strategy for identifying risk genes is to identify and map quantitative intermediate phenotypes or endophenotypes.
Objective: To adjudicate neurocognitive endophenotypes for bipolar disorder.
Social and clinical comparison between schizophrenia and bipolar disorder type I with psychosis in Costa Rica.
Soc Psychiatry Psychiatr Epidemiol
June 2010
Article Synopsis
- - Schizophrenia (SC) and bipolar disorder (BP) are serious mental health disorders that may either be distinct conditions or exist on a continuum with similar causes.
- - A study compared 84 individuals with SC and 84 with BP in Costa Rica, finding notable differences in social outcomes, such as marital and employment status, but similarities in education and onset age.
- - The study concluded that SC and BP show distinct social and functional declines, supporting earlier theories that differentiate these disorders based on chronicity and periodicity.
Background: Elevated levels of impulsivity and increased risk taking are thought to be core features of both bipolar disorder (BD) and addictive disorders. Given the high rates of comorbid alcohol abuse in BD, alcohol addiction may exacerbate impulsive behavior and risk-taking propensity in BD. Here we examine multiple dimensions of impulsivity and risk taking, using cognitive tasks and self-report measures, in BD patients with and without a history of alcohol abuse.
View Article and Find Full Text PDFBackground: Psychotic bipolar disorder may represent a neurobiologically distinct subgroup of bipolar affective illness. We sought to ascertain the profile of cognitive impairment in patients with bipolar disorder and to determine whether a distinct profile of cognitive deficits characterizes bipolar patients with a history of psychosis.
Methods: Sixty-nine outpatients with bipolar I disorder (34 with a history of psychotic symptoms and 35 with no history of psychosis) and 35 healthy comparison subjects underwent a comprehensive neurocognitive battery.