Publications by authors named "Marcel P M ten Tusscher"
Bilateral Optic Disc Swelling with Persistent Visual Loss in Anemia: Case Report.
Case Rep Ophthalmol
October 2023
A 56-year-old man with a medical history of alcoholic cirrhosis presented with acute bilateral loss of vision. On admission, the patient had pale skin and low arterial pressure. Ophthalmic examination demonstrated a visual acuity of 6/9 in the right eye and the absence of light perception in the left.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates the role of interhemispheric connections in human binocularity, focusing on the corpus callosum (CC) in individuals with infantile esotropia (IE).
- Using diffusion tensor imaging, researchers found that subjects with IE had a higher number of callosal fibers linking visual cortical areas compared to controls, indicating significant interhemispheric connectivity differences.
- The findings suggest that abnormal pruning of transcallosal fibers during development in IE alters the visual pathways, emphasizing the importance of the CC in developing binocular vision.
Purpose: Two Caucasian Belgian families were diagnosed with autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS). The ophthalmological findings in both ARSACS disease and carriers are described.
Methods: In addition to a complete ophthalmological assessment, in both patients and carriers, spectral-domain Optical Coherence Tomography scans of the peri-papillary retinal nerve fiber layer were performed.
Article Synopsis
- A 72-year-old woman experienced a painful right eye, with symptoms including redness and swelling in the conjunctiva.
- During a slit lamp exam, she was initially treated with artificial tears, but after a month a firm mass appeared near her lacrimal gland.
- Imaging revealed infiltrative structures in both orbits, and biopsies confirmed that the conjunctival swelling and lacrimal gland contained metastases from lobular breast carcinoma.
A closer look at the evolution of the eye and the brain provides a possible explanation for both the origin of infantile esotropia and its motor characteristics. In the course of evolution, the eyes have moved from a lateral to a frontal position. Consequently, the monocular visual fields started to overlap resulting in a binocular visual field.
View Article and Find Full Text PDFArticle Synopsis
- Dissociated vertical divergence (DVD) is prevalent in infantile strabismus, where eye alignment differs based on fixation.
- The theory that DVD originates from a primitive fish reflex is contradicted by neuroanatomical evidence.
- A new hypothesis suggests that the lack of binocular development in the cortex leads to separate activation of subcortical pathways, impacting eye movement coordination.