Fighting Antimicrobial Resistance: Innovative Drugs in Antibacterial Research.

In the fight against bacterial infections, particularly those caused by multi-resistant pathogens, the need for new antibacterials is undoubted in scientific communities. and is by now also widely perceived by the general population. However, the antibacterial research landscape has changed considerably over the past years.

A fluorometric assay to determine labile copper(II) ions in serum.

Labile copper(II) ions (Cu) in serum are considered to be readily available for cellular uptake and to constitute the biologically active Cu species in the blood. It might also be suitable to reflect copper dyshomeostasis during diseases such as Wilson's disease (WD) or neurological disorders. So far, no direct quantification method has been described to determine this small Cu subset.