Publications by authors named "Marcel Flemming"

Hydrodistillation and solid-liquid extraction with organic solvents or supercritical CO are standard technologies for natural product manufacturing. Within this technology, portfolio pressurized hot water technology is ranked as a green, sustainable, resilient, kosher and halal manufacturing process. Essential for sustainability is energy integration for heating and cooling the auxiliary water as well as product concentration without evaporation but with the aid of low energy consuming ultra- and nanofiltration membrane technology.

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The proazulene matricine (1) is present in chamomile flower heads and has been proven to exhibit strong in vivo anti-inflammatory activity. In contrast to other secondary metabolites in chamomile preparations like its degradation product chamazulene (2), no plausible targets have been found to explain this activity. Therefore we revisited 1 regarding its in vitro anti-inflammatory activity in cellular and molecular studies.

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Films with specific nanoroughness were designed by "virtual coating" to yield ultrahydrophobicity while the light scatter remained below an application-relevant threshold. Examples of coating experiments demonstrate the realization of predicted properties.

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Optical coatings with enhanced roughness offer promising prospects for ultrahydrophobic transparent surfaces with controlled scatter losses. Our approach links roughness characteristics with both wetting behavior and scattering. Experiments with rough oxide layers yielded surfaces with a high water contact angle.

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