Dimercaptosuccinic acid scintigraphy vs. ultrasound for renal parenchymal defects in children.

Introduction: Dimercaptosuccinic acid (DMSA) scintigraphy is the gold standard in the evaluation of renal parenchymal defects and is widely used in the pediatric population. As more recent ultrasound equipment was purchased at our tertiary pediatric centre, our objective was to evaluate if renal ultrasound (US) results are equivalent or sufficient when compared to DMSA scintigraphy in the assessment of renal anomalies.

Methods: The charts of all 463 patients who underwent DMSA scintigraphy between January 2009 and May 2014 at our pediatric tertiary centre were reviewed.

Identifying which treated hypertensive patients without known coronary artery disease should be tested for the presence of myocardial ischemia by perfusion imaging.

Stress dipyridamole technetium-99(m) sestamibi single photon emission computed tomographic imaging was used to study myocardial perfusion in 1116 hypertensive patients without known coronary artery disease (CAD). The test confirmed the presence of CAD in 28.9% of patients.

Noninvasive detection of silent coronary artery disease in patients with essential hypertension, alone or associated with type 2 diabetes mellitus, using dipyridamole stress 99mtechnetium-sestamibi myocardial perfusion imaging.

Background: Coronary artery disease (CAD) is the leading cause of morbidity and mortality in hypertensive and diabetic patients. Early diagnosis of CAD and identification of high-risk subgroups, followed by appropriate therapy, may therefore enhance survival.

Objectives: To prospectively establish the prevalence of silent CAD in asymptomatic patients with essential hypertension (EH), and to establish to what extent type 2 diabetes mellitus (DM) modifies the prevalence and severity of silent CAD in these patients.

Real-time imaging of myoblast transplantation using the human sodium iodide symporter.

The quantification of the graft success is a key element to evaluate the efficiency of cellular therapies for several pathologies such as Duchenne muscular dystrophy. This study describes an approach to evaluate the success of myoblast transplantation (i.e.

Magnetic resonance-guided percutaneous cryosurgery of breast carcinoma: technique and early clinical results.

Purpose: This phase I study was designed to demonstrate the feasibility, safety, efficacy and predictability of percutaneous cryosurgery, guided under magnetic resonance (MR) imaging, in the treatment of invasive breast carcinoma.

Patients And Methods: Under the guidance of near-real-time T1-weighted FSE images of a 0.5-T open-configuration MR system, percutaneous cryosurgery was performed in 25 patients with operable invasive breast carcinoma, 4 weeks prior to their scheduled mastectomy.

The clinical meaning of gastric-wall hyperactivity observed on sestamibi cardiac single-photon emission computed tomography.

Objective: To evaluate prospectively the incidence and clinical meaning, if any, of gastric-wall hyperactivity observed on sestamibi cardiac single-photon emission computed tomography (SPECT). This phenomenon is completely different from the well-known intraluminal gastric reflux of sestamibi.

Methods: A group of 819 patients who underwent sestamibi cardiac SPECT was studied from January 2000 to October 2000.

Early transient hydronephrosis after laparoscopic aortobifemoral bypass grafting.

Hydronephrosis early after aorto-bifemoral bypass grafting is probably an underestimated complication. We describe early and transient hydronephrosis that developed in two patients after totally laparoscopic aorto-bifemoral bypass surgery to treat aortoiliac occlusive disease. A conservative approach to treatment was adopted, and both patients recovered.

Does bone change after biliopancreatic diversion?

This prospective study evaluated bone changes after biliopancreatic diversion (BPD) consisting of a distal gastrectomy, a 250 cm alimentary channel, and a 50 cm common channel. Thirty-three consecutive patients had clinical, biochemical, and bone mineral density analysis before surgery and 4 and 10 years after surgery. Iliac crest bone biopsies and special tests including parathyroid hormone (PTH), 25-hydroxyvitamin D (25-OH-D), 1,25-dihydroxyvitamin D (1,25-OH(2)-D), bone-specific alkaline phosphatase (BAP), and osteocalcin were obtained at surgery and 4 years postoperatively.

Association of physical activity and bone: influence of vitamin D receptor genotype.

Purpose: The aim of the study was to investigate the interaction between leisure physical activity and a BsmI polymorphism at the vitamin D receptor (VDR) gene on the modulation of bone mineral density (BMD).

Methods: We studied 575 unrelated healthy postmenopausal women. Lumbar spine and femoral neck BMD were measured by dual-energy x-ray absorptiometry (DXA), and results were expressed as age-and-weight-adjusted (Z-score).