Publications by authors named "Marcel Donze"
Article Synopsis
- Red blood cells (RBCs) face oxidative stress from internal and external sources, primarily through the autoxidation of oxyhemoglobin that produces harmful oxidants like superoxide and hydrogen peroxide.
- Effective antioxidant systems, including key enzymes like peroxiredoxin 2 and glucose metabolism for NADPH production, protect RBCs from damage and help maintain vascular health.
- Conditions such as glucose-6-phosphate dehydrogenase deficiencies, hemoglobinopathies, and storage lesions in transfused RBCs can lead to overwhelming oxidative stress, highlighting the importance of redox balance in these cells.
