Publications by authors named "Marcantonio O"

Article Synopsis
  • Skin local reactions to mRNA COVID-19 vaccines may be linked to vaccine excipients, prompting a study on skin testing for delayed reactions.
  • The study involved healthcare workers with adverse skin reactions to the vaccines, testing them with various excipients and comparing results to a control group without reactions.
  • Results showed a high percentage of delayed skin reactions to PEG-2000 in those with delayed large local reactions, suggesting PEG's potential role in these skin reactions, while testing for other excipients was not significant.
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A 59-year-old woman presented with a persistent eruption manifested as multiple agminated miliary facial papules. Histopathological examination showed prominent nodular dermal lymphoid infiltrates with hyperplastic follicles that were initially interpreted as B-cell reactive lymphoid hyperplasia. Several years later, an additional biopsy showed a dense perifollicular infiltrate with reactive primary and secondary follicles.

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A 57-year-old woman presenting an acquired and persisting palmoplantar keratoderma associated with primary biliary cholangitis is reported. Treatment with oral ursodeoxycholic acid was prescribed, and a complete and persistent resolution of skin lesions was noted. This observation seems to support that acquired palmoplantar keratoderma is an uncommon cutaneous manifestation of primary biliary cholangitis.

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Background: Cutaneous reactions after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines are poorly characterized.

Objective: To describe and classify cutaneous reactions after SARS-CoV-2 vaccination.

Methods: A nationwide Spanish cross-sectional study was conducted.

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