Treatment response and 5-year distant metastasis-free survival outcome in breast cancer patients after the use of MammaPrint and BluePrint to guide preoperative systemic treatment decisions.

Aim: In the prospective neoadjuvant NBREaST II study, we measured the response to preoperative treatment and 5-year survival outcome in the molecular subgroups as determined by combining the MammaPrint and BluePrint.

Methods: Between 2012 and 2016 we included 256 patients for whom MammaPrint and BluePrint were performed on pre-treatment core needle biopsies. The primary objective of the NBREaST II trial was to measure chemosensitivity or endocrine sensitivity in the molecular subgroups.

Hospital Teaching Status and Patients' Outcomes After Colon Cancer Surgery.

Background And Objectives: It is increasingly accepted that quality of colon cancer surgery might be secured by combining volume standards with audit implementation. However, debate remains about other structural factors also influencing this quality, such as hospital teaching status. This study evaluates short-term outcomes after colon cancer surgery of patients treated in general, teaching or academic hospitals.

Traumatic abdominal wall hernia, easily missed.

A 30-year-old male was diagnosed with a disruption of the musculofibrotic abdominal wall as a result of a blunt trauma 3 years after the injury. His traumatic abdominal wall hernia (TAWH) was initially missed on physical examination and computed tomography. The patient presented now with a lump in the left flank after a period of intended weight loss.