Synopsis of recent research by authors named "Marc W Retter"
- Marc W Retter's recent research primarily focuses on innovative treatments for cancer, particularly through the development of bispecific antibodies that engage T cells to target tumor cells, highlighting their clinical potential, pharmacokinetic properties, and mechanisms of action.
- His work includes studies on T-cell engaging bispecific antibodies such as odronextamab and BCMAxCD3, emphasizing their effectiveness in hematological malignancies and the translational insights necessary for first-in-human clinical studies.
- Additionally, Retter investigates therapeutic combinations (e.g., pozelimab and cemdisiran) and novel agents targeting complement activation in diseases like PNH, demonstrating a broad interest in enhancing cancer immunotherapy efficacy and applying pharmacological principles to improve treatment outcomes.
