Publications by authors named "Marc Machaalani"
Article Synopsis
- The commentary discusses an article by Correa et al that investigates how circulating tumor DNA can be linked to the prognosis of patients with renal cell carcinoma.
- It highlights the importance of using circulating tumor DNA as a potential biomarker to predict patient outcomes in this type of cancer.
- The findings suggest that monitoring circulating tumor DNA levels may help improve treatment strategies and patient management in renal cell carcinoma.
Background: Telomerase reverse transcriptase (TERT) gene promoter mutations have been explored, as biomarkers of improved survival for patients with cancer receiving immune checkpoint inhibitors. We sought to investigate their prevalence by race and sex across different cancer types to inform patient selection in clinical trials.
Results: In this observational study, 31 925 patients with cancer underwent next-generation sequencing of their tumors with 88% (27 970) patients self-reported being Whites, 7.
Cancer research activity in the Arab world: a 15-year bibliometric analysis.
J Egypt Public Health Assoc
November 2022
Background: The Arab region comprises 22 countries located in the Middle East and North Africa, sharing cultural and linguistic ties. Arab countries have continued to lag in terms of biomedical research compared to other nations for several past decades. Cancer is a major public health concern, being the second leading cause of death globally.
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- * CVD patients were older and showed better knowledge and attitudes towards CVD compared to non-CVD individuals; however, their practical application of that knowledge was lower.
- * The study highlights the need for targeted educational campaigns in Lebanon to improve KAP about CVD, especially focusing on factors like educational level, region, and smoking habits, which significantly influence KAP scores.
Background And Objectives: Hypertension (HTN) is a major health concern that leads to cardiovascular disease and premature death. Assessing HTN knowledge, attitude, and practice (KAP) is crucial for controlling HTN. This study aimed to determine HTN KAP among hypertensive patients residing in Lebanon.
View Article and Find Full Text PDFColorectal cancer (CRC) is the third most common cancer in the world. Despite improvement in standardized screening methods and the development of promising therapies, the 5-year survival rates are as low as 10% in the metastatic setting. The increasing life expectancy of the general population, higher rates of obesity, poor diet, and comorbidities contribute to the increasing trends in incidence.
View Article and Find Full Text PDFBackground: The Arab world consists of 22 countries situated in the Middle East and North Africa, tied together by linguistic and cultural bonds. Over numerous past decades, this region tended to fall behind regarding biomedical research. Organ, tissue, and cell transplantation are life-saving and life-improving treatments for various diseases.
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