Publications by authors named "Marc Garcia-Lorenzo"
Article Synopsis
- Parvovirus B19 (PVB19) is a small virus that often causes mild or no symptoms, but in children, it can lead to various conditions like rashes and joint pain.
- Three pediatric cases from Milan in March 2024 showed different manifestations of PVB19, including rashes and low platelet counts.
- The findings stress the virus’s potential complications, highlight the need for careful diagnosis during outbreaks, and point out the importance of understanding PVB19's epidemiological patterns for better management in children.
Aim: The aim of this review was to summarise the most recent evidence about the use of omics-based techniques as an instrument for a more rapid and accurate characterisation of respiratory tract infections, neurological infections and sepsis in paediatrics.
Methods: We performed a narrative review using PubMed and a set of inclusion criteria: English language articles, clinical trials, meta-analysis and reviews including only paediatric population inherited to this topic in the last 15 years.
Results: The examined studies suggest that host gene expression signatures are an effective method to characterise the different types of infections, to distinguish infection from colonisation and, in some cases, to assess the severity of the disease in children.
Multisystem inflammatory syndrome in children (MIS-C) is a rare but severe disease temporarily related to SARS-CoV-2. We aimed to describe the epidemiological, clinical, and laboratory findings of all MIS-C cases diagnosed in children < 18 years old in Catalonia (Spain) to study their trend throughout the pandemic. This was a multicenter ambispective observational cohort study (April 2020-April 2022).
View Article and Find Full Text PDFCharacterization of severe asthma in the pediatric population.
Allergol Immunopathol (Madr)
October 2021
Introduction And Objectives: Relationship between the causal mechanisms of pediatric severe asthma and severity of symptoms would be helpful for developing personalized strategies for treatment and prevention.
Materials And Methods: For this study, 698 medical histories of asthmatics between 6 and 18 years of age were reviewed in a period of 2 years. Variables analyzed were: age, sex, ethnicity, perinatological history, allergy history, asthma predictive index (API), exposure to tobacco, heavy traffic or epithelium, lung function, age of onset of symptoms, hospitalization admissions/PICU, systemic corticosteroids, daily symptoms control, device prescribe for daily control, and adherence.