Publications by authors named "Marc Fischler"

Objective: Mean arterial pressure is widely used as the variable to monitor during anesthesia. But there are many other variables proposed to define intraoperative arterial hypotension. The goal of the present study was to search arterial pressure variables linked with prolonged postoperative length of stay (pLOS).

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Purpose: Nausea and vomiting complicating chemotherapy (CINV) remain side effects despite preventive and curative treatments. We hypothesize that acupuncture (ACU), auriculotherapy (AUR), and their combination (ACU-AUR), could decrease, compared to usual treatment (UT), the intensity of acute nausea in patients already treated according to the antiemetic guidelines and presenting nausea with or without vomiting in the earlier cycle.

Methods: In this multicenter study, patients were treated just before chemotherapy according to randomization.

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This bicentric retrospective cohort study evaluates reversal of muscle relaxation in real life achieved either by neostigmine or sugammadex in two hospitals using different types of neuromuscular monitoring (acceleromyography and kinemyography). The research question concerns compliance with recommendations. Patients who underwent an abdominal surgery under general anesthesia in the period from January 2017 through December 2020 with a neuromuscular block with rocuronium were included in the study.

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Article Synopsis
  • - The study aimed to assess whether inflammatory cell ratios, particularly the neutrophil-to-lymphocyte ratio (NLR), have any correlation with postoperative complications in patients undergoing lobectomy surgery.
  • - Conducted at Foch University Hospital in France, this retrospective study analyzed data from 208 patients who had scheduled lobectomies from January 2018 to September 2021.
  • - Results showed no significant link between any of the inflammatory ratios and the occurrence of major complications or longer hospital stays, indicating these ratios aren't effective for predicting risks in elective lobectomy patients.
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Background: The estimation of gastric content in third trimester pregnant women has already been studied, conclusions remain contradictory. The aim of this study was to compare gastric content in pregnant and non-pregnant women using gastric ultrasound. We performed an observational two-center study of women scheduled for a cesarean section (CS group) and of non-pregnant women scheduled for hysteroscopy (HS group).

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Purpose: Post-thoracotomy pain syndrome (PTPS) and chronic postsurgical neuropathic pain (CPNP) were evaluated 4 months after thoracic surgery whether the approach was a posterolateral (PL) incision or the less invasive axillary (AX) one.

Methods: Patients, 79 in each group, undergoing a thoracotomy between July 2014 and November 2015 were analyzed 4 months after surgery in this prospective monocentric cohort study.

Results: More PL patients suffered PTPS (60.

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Use of auriculotherapy to prevent episodic migraine pain has seldom been reported. The aim of this open study was to show that three sessions of auriculotherapy, 1 month apart, using semi-permanent needles decrease frequency and intensity of an attack in patients presenting episodic migraine. A total of 90 patients were randomized to the treatment group (AUR group,  = 58) or the control group (C group,  = 32).

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Objective: Life expectancy for lung-transplant patients, especially those with cystic fibrosis (CF), is leading increasingly to more retransplantations.

Design: Retrospective monocentric cohort study.

Setting: Foch University Hospital, Suresnes, France.

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Transplanted patients could benefit from complementary techniques. This prospective single-center, open study, performed in a tertiary university hospital, evaluates the appropriation and efficacy of a toolbox-kit of complementary techniques. Self-hypnosis, sophrology, relaxation, holistic gymnastics, and transcutaneous electric nerve stimulation (TENS) were taught to adult patients scheduled for double-lung transplantation.

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Article Synopsis
  • The study aimed to objectively assess postoperative mobility in patients after mini-invasive lung surgery using accelerometers instead of relying solely on patient self-reports.
  • Results showed no significant change in daily steps during the first four days post-surgery, but improvements were observed in light physical activity duration and a decrease in prolonged sedentary bouts.
  • Overall, patients found the accelerometer acceptable, with a high median rating, and only three patients experienced major complications during the study.
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The management of lung transplant patients has continued to evolve in recent years. The year 2021 was marked by the publication of the International Consensus Recommendations for Anesthetic and Intensive Care Management of Lung Transplantation. There have been major changes in lung transplant programs over the last few years.

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In this study, we aimed to assess the efficacy of high-flow nasal oxygen (HFNO) to maintain blood peripheral oxygen saturation (SpO2) in patients undergoing suspension laryngoscopy under general anesthesia. Adult patients were included in this bicenter study. After face-mask oxygenation, HFNO at a flow rate of 70 L min and fraction of inspired oxygen 100% was initiated at loss of consciousness.

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Background: Endoscopic transsphenoidal surgery is the most common technique for the resection of pituitary adenoma. Data on factors associated with extended hospital stay after this surgery are limited. We aimed to characterize the relationship between preoperative medications and the risk of prolonged postoperative length of stay after this procedure.

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Less-invasive thoracotomies may reduce early postoperative pain. The aims of this study were to identify pain trajectories from postoperative days 0-5 after posterolateral and axillary thoracotomies and to identify potential factors related to the worst trajectory. Patients undergoing a posterolateral (92 patients) or axillary (89 patients) thoracotomy between July 2014 and November 2015 were analyzed in this prospective monocentric cohort study.

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Background: Although diabetic gastroparesis could be responsible for delayed gastric emptying, there is conflicting evidence about the volume of gastric content in diabetic patients after preoperative fasting. We hypothesized that diabetic patients had an increased gastric content before anesthesia induction despite the following of fasting recommendations. We used ultrasound assessment of gastric content to evaluate this risk.

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Objective: Hypnosis can reduce pain and anxiety in surgical patients. This study aimed to demonstrate that implementing self-hypnosis in the setting of lung transplantation could improve patients' pain and quality of life.

Design: A randomized, single-center study.

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Ultrasound-guided hydrodissection with 5% dextrose in water (DW5) creates a peri-nervous compartment, separating the nerve from the neighboring anatomical structures. The aim of this randomized study was to determine the minimum volume of lidocaine 2% with epinephrine 1:200,000 required when using this technique to achieve an effective median nerve block at the elbow in 95% of patients (MEAV95). Fifty-two patients scheduled for elective hand surgery received an ultrasound-guided circumferential perineural injection of 4 ml DW5 and an injection of local anesthetic (LA) following a biased coin up-and-down sequential allocation method.

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Article Synopsis
  • - The study aimed to investigate whether using videolaryngoscopy (specifically the McGrath Mac) improves the practice and ease of tracheal intubation compared to traditional methods.
  • - In a randomized trial with 300 patients (271 randomized and 256 analyzed), results showed no significant reduction in the need for assistance during intubation in the video group (36.1%) compared to the no-video group (45.5%), but the video group had better glottic opening scores and overall ease of intubation ratings.
  • - Despite some improvements noted in secondary outcomes, including ease of intubation and glottic visibility, the overall requirement for assistance and intubation difficulty were similar between the
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We aimed to demonstrate the antalgic effectiveness of Scenar (Self-Controlled Electro Neuro Adaptative Regulation) in patients experiencing low back and neck pain. Sixty patients were included and equally assigned by randomization to a Scenar-On group and to a Scenar-Off group (sham group). All patients received a 20 min application of Scenar on the area where they experienced pain.

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  • - The study aimed to determine if intraoperative blood lactate levels can predict grade-3 primary graft dysfunction (PGD3-T72) after double-lung transplantation, contrasting with previously known factors.
  • - Analyzing data from 449 patients, researchers found that blood lactate levels increased during surgery, with higher levels associated with PGD3-T72. The critical threshold identified was 2.6 mmol/L, which could effectively predict the risk of PGD3-T72.
  • - Ultimately, patients who maintained blood lactate levels below this threshold after surgery were less likely to experience severe graft dysfunction, indicating the potential usefulness of monitoring lactate levels in clinical settings.
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: Postoperative hypotension associated with postoperative morbidity and early mortality has been studied previously. Hypertension and other hemodynamic, respiratory, and temperature abnormalities have comparatively understudied during the first postoperative days. : This bi-centre observational cohort study will include 114 adult patients undergoing non-cardiac surgery hospitalized on an unmonitored general care floor and wearing a multi-signal wearable sensor, allowing remote monitoring ( Biobeat Technologies Ltd, Petah Tikva, Israel).

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The preoperative period may be an opportune period to optimize patients' physical condition with a multimodal preoperative program. The impact of a "prehabilitation" program on elderly patients is discussed. This mono-center observational cohort study included consecutively 139 patients planned for major abdominal and thoracic surgery, with 44 in the control group (age < 65) and 95 in the elderly group (age > 65).

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