Change in coronary flow reserve on transthoracic Doppler echocardiography after a single high-fat meal in young healthy men.

Background: High-fat meals and elevated triglyceride levels are associated with cardiovascular disease. In recent studies of brachial artery vasoactivity, a single high-fat meal reduced endothelial function in young healthy men. It is unknown whether coronary microcirculation is affected after high-fat meals.