Publications by authors named "Marc Antoine Delbarre"
Article Synopsis
- - The study investigates the relationship between transthyretin wild-type cardiac amyloidosis (TTRwt-CA) and aortic stenosis (AS), proposing a bidirectional connection where each condition may influence the other and lead to systemic manifestations, including carpal tunnel syndrome (CTS).
- - In a sample of 411 TTRwt-CA patients, approximately 70% had CTS, which correlated with younger age, more severe cardiac remodeling, and a higher frequency of extracardiac symptoms, while AS occurred in 21% of those with CTS and 31% without.
- - The research indicates that CTS may differentiate two phenotypes of TTRwt-CA: one associated with systemic involvement and poorly calcified low-flow
Background: Cardiac uptake on technetium-99m whole-body scintigraphy (WBS) is almost pathognomonic of transthyretin cardiac amyloidosis. The rare false positives are often related to light-chain cardiac amyloidosis. However, this scintigraphic feature remains largely unknown, leading to misdiagnosis despite characteristic images.
View Article and Find Full Text PDFAims: Iron deficiency (ID) is common in patient with chronic heart failure (HF) and has been widely studied. In contrast, data concerning ID in cardiac amyloidosis (CA) are limited. Amyloidosis is a severe and fatal systemic disease, characterized by an accumulation of amyloid fibrils in various tissues/organs, including nerves, kidneys, gastrointestinal tract, and heart.
View Article and Find Full Text PDFBackground: We assesse the evolution and prognostic value of N-terminal pro-brain natriuretic peptide (NT-proBNP) and high-sensitivity troponin T (cTnT-HS) in transthyretin amyloid cardiomyopathy (ATTR-CA) before and after tafamidis treatment.
Methods And Results: 454 ATTR-CA patients without tafamidis (Cohort A) and 248 ATTR-CA with tafamidis (Cohort B) were enrolled. Event-free survival (EFS) events were death, heart transplant, or acute heart failure.