Publications by authors named "Marandyuk B"
Objective: We investigated how electroencephalography (EEG) quantitative measures and dysglycemia relate to neurodevelopmental outcomes following neonatal encephalopathy (NE).
Methods: This retrospective study included 90 neonates with encephalopathy who received therapeutic hypothermia. EEG absolute spectral power was calculated during post-rewarming and 2-month follow-up.
Article Synopsis
- Infants born to diabetic mothers (IDM) are more likely to experience complications and poor short-term outcomes after hypoxic-ischemic encephalopathy (HIE) compared to those born to non-diabetic mothers.
- A study involving 102 term neonates with HIE showed that those exposed to maternal diabetes had lower gestational ages, higher birth weights, and required longer ventilation and NICU stays.
- Maternal diabetes increased the risk of adverse outcomes, including a higher likelihood of death or abnormal neurological findings at discharge, highlighting the need for better diabetes management during pregnancy.
Fetal cardiac and neonatal cerebral hemodynamics and oxygen metabolism in transposition of the great arteries.
Ultrasound Obstet Gynecol
March 2023
Objectives: Hemodynamic abnormalities and brain development disorders have been reported previously in fetuses and infants with transposition of the great arteries and intact ventricular septum (TGA-IVS). A ventricular septal defect (VSD) is thought to be an additional risk factor for adverse neurodevelopment, but literature describing this population is sparse. The objectives of this study were to assess fetal cardiac hemodynamics throughout pregnancy, to monitor cerebral hemodynamics and oxygen metabolism in neonates, and to compare these data between patients with TGA-IVS, those with TGA-VSD and age-matched controls.
View Article and Find Full Text PDFBackground: Therapeutic hypothermia (TH) without sedation may lead to discomfort, which may be associated with adverse consequences in neonates with hypoxic-ischemic encephalopathy (HIE). The aim of this study was to assess the association between level of exposure to opioids and temperature, with electroencephalography (EEG) background activity post-TH and magnetic resonance imaging (MRI) brain injury in neonates with HIE.
Methods: Thirty-one neonates with mild-to-moderate HIE who underwent TH were identified.
Purpose: Children with complex congenital heart disease (CHD) experience high incidence of perioperative seizures. Population-based studies also report high epilepsy co-morbidity in CHD. Given the increasing survival of patients with CHD and the interference of seizures and epilepsy with the long-term outcomes, characterizing them in this population is of high relevance.
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