Predictive Ability of 10-Minute Apgar Scores for Mortality and Neurodevelopmental Disability.

Objective: To test the hypothesis that an Apgar score at 10 minutes is independently predictive for death or moderate or severe disability.

Methods: A secondary analysis of the Optimizing Cooling Trial (NCT01192776) including 347 infants with ≥36 weeks' gestational age at birth and hypoxic-ischemic encephalopathy and 18- to 22-month outcomes from 18 US centers in the National Institute of Child Health and Human Development Neonatal Research Network. The primary outcome was the composite of death or moderate/severe disability at 18 to 22 months of age.