Objective: 1. To study the clinical profile, progression and outcome of GBS during peripartum period in a tertiary care hospital. 2.
View Article and Find Full Text PDFUnlabelled: Central nervous system tuberculosis (TB) is the most severe extra pulmonary TB having a high mortality and morbidity.
Objective: To study the various clinical, biochemical, and radiological spectrum of intracranial TB.
Materials And Method: Ninety-three patients were enrolled in this prospective study after ethical clearance and consent from August 2013 to May 2015.
Background: The discovery of antibodies against aquaporin-4 and evolving concepts of noncompressive myelopathies in the 21 century have made a major impact on the etiological profile of these diseases, with few cases turning out to be idiopathic.
Objective: To find causes of noncompressive myelopathy in a tertiary care hospital of Northeast India.
Materials And Methods: An observational study was carried out in the Neurology Department of Gauhati Medical College, Guwahati, from September 2013 to February 2016.
It has been just 7 years since the discovery of anti-NMDAR encephalitis as distinct immune-mediated encephalitis and we have such cases being reported from our country. Herein, we describe a case of a 13-year-old girl who had relapsing encephalitis consisting of multiple types of difficult-to-control seizures, abnormal behavior, language disintegration, memory loss and abnormal movements eight years after the first clinical attack. In 2005, when she was 5 yearsold, anti-NMDAR encephalitis was not yet discovered and she was provisionally diagnosed as a case of viral encephalitis.
View Article and Find Full Text PDFIntroduction: Moyamoya disease is a chronic progressive cerebrovascular disorder, characterized by stenosis or occlusion of bilateral internal carotid arteries (ICAs), anterior cerebral arteries (ACAs) and middle cerebral arteries (MCAs), accompanied by a collateral network of vessels formed at the base of the brain. Ischemia and intracranial hemorrhage are the common typical manifestations. However moyamoya disease has been associated with atypical presentations like headache, seizures and involuntary movements.
View Article and Find Full Text PDFIntroduction: MAJOR CATEGORIES OF ENDOCRINE MYOPATHY INCLUDE THOSE ASSOCIATED WITH: Adrenal dysfunction (as in Cushing's disease or steroid myopathy); thyroid dysfunction (as in myxedema coma or thyrotoxic myopathy); vitamin D deficiency; parathyroid dysfunction; and pituitary dysfunction. Steroid myopathy is the most common endocrine myopathy.
Objective: To study the etiology, varied presentations, and outcome after therapy of patients with endocrine myopathies.
Ann Indian Acad Neurol
April 2013
Background: Acute hypokalemic paralysis, characterized by acute flaccid paralysis is primarily a calcium channelopathy, but secondary causes like renal tubular acidosis (RTA), thyrotoxic periodic paralysis (TPP), primary hyperaldosteronism, Gitelman's syndrome are also frequent.
Objective: To study the etiology, varied presentations, and outcome after therapy of patients with hypokalemic paralysis.
Materials And Methods: All patients who presented with acute flaccid paralysis with hypokalemia from October 2009 to September 2011 were included in the study.
Duchenne muscular dystrophy (DMD) is an X-linked recessive disorder that affects 1 in 3,500 males and is caused by mutations in the dystrophin gene. In this paper, we have reported DNA analysis of DMD patients by multiplex polymerase chain reaction (PCR) from various states of northeast India. Of the 69 clinically suspected patients of DMD, deletion was detected by multiplex PCR in 49 (71%) patients.
View Article and Find Full Text PDFBackground: Epilepsia partialis continua (EPC), is a subtype of status epilepticus, have a varied spectrum of etiology and the out-come depends on the etiology.
Aims And Objectives: The present study is aimed to analyze the clinical characteristics and outcome.
Materials And Methods: This is a prospective analysis of 17 patients admitted to our center between August 2010 and April 2012.
Introduction: Japanese encephalitis (JE) is mosquito-borne flaviviral encephalitis that remains to be a major health problem in India--it still continues to cause havoc in many parts of the country. We undertook the study to analyze the clinical and radiological spectrum of JE in adults and children.
Method: This prospective study consists of 148 patients with JE.
Here we present the case of a 17-year-old girl belonging to an ethnic tribe (Bodo tribe) of Assam, presenting with bilateral cerebellar signs and with history suggestive of an autosomal dominant pattern of inheritance, who was found to have spinocerebellar ataxia 7 on genetic testing. This case throws light on the probability of more such cases in the multi-ethnic society of the North-Eastern Indian states, which are not studied or reported till date.
View Article and Find Full Text PDFBackground: Symptomatic neurosyphilis (NS) can have varied syndromic presentations: Meningitis, meningovascular and parenchymatous involvement.
Aims: To evaluate the different types of clinical syndrome of NS in a tertiary care hospital.
Material And Methods: This was a study of clinical profile of 16 patients with NS, seen in between August 2008 and December 2010.