Publications by authors named "Mara Disabato"

Background & Aims: In France, liver grafts that have been refused at least 5 times can be "rescued" and allocated to a centre which chooses a recipient from its own waiting list, outside the patient-based allocation framework. We explored whether these "rescued" grafts were associated with worse graft/patient survival, as well as assessing their effect on survival benefit.

Methods: Among 7,895 candidates, 5,218 were transplanted between 2009 and 2014 (336 centre-allocated).

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Article Synopsis
  • The study examines liver transplants using "Rescue" allocation (RA) versus standard allocation (SA) in France, finding that RA livers can increase the available donor pool by 25%.
  • It analyzed 249 cases from 2011 to 2015, revealing no significant differences in complications, graft function, or survival rates between RA and SA graft recipients despite differences in donor age and ischemia time.
  • The findings suggest that RA livers can be safely transplanted to appropriate patients, allowing for greater utilization of available organs in liver transplantation.
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Background: Emergency digestive surgery is being increasingly performed in elderly patients. The aim of the present study was to identify the predictors of mortality and morbidity following emergency digestive surgery in patients aged 80 years and older.

Methods: A single-center retrospective review was performed of consecutive patients aged ≥65 years operated for a digestive surgical emergency between January 2011 and December 2013.

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Background: Control of warm ischemia (WI) lesions that occur with donation after circulatory death (DCD) would significantly increase the donor pool for liver transplantation. We aimed to determine whether a novel, oxygenated and hypothermic machine perfusion device (HMP Airdrive system) improves the quality of livers derived from DCDs using a large animal model.

Methods: Cardiac arrest was induced in female large white pigs by intravenous injection of potassium chloride.

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This study compared robotic (RR) and laparoscopic resection (LR) for primary gastrointestinal stromal tumors (GISTs) of the stomach >5 cm. Twelve consecutive patients who underwent RR from 2012 to 2015 were matched for tumor size and location with 24 patients who underwent LR from 2000 to 2012. The median tumor size was 7.

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Purpose: The aim of the study was to compare the short- and long-term outcomes of laparoscopic extended right colectomy (ER) versus laparoscopic left colectomy (LC) for splenic flexure carcinomas.

Methods: Patients with stage 0-III adenocarcinoma of the splenic flexure who underwent laparoscopy between 2000 and 2013 were identified from a prospectively maintained database. Twenty-seven patients who underwent ER were matched by age, gender, BMI, ASA score, and tumor stage with 27 patients who underwent LC.

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Objectives: The aim of the study was to compare the long-term oncologic results of laparoscopic liver resection (LLR) versus open liver resection (OLR) for colorectal liver metastasis (CRLM) using a propensity score analysis.

Subjects And Methods: This propensity score matching (PSM) study was based on a prospective database of a single tertiary-care center. Patients with primarily resectable CRLM were selected for a 1:1 PSM between LLR and OLR.

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Right colon cancer rarely presents as an emergency, in which bowel occlusion and massive bleeding are the most common clinical presentations. Although there are no definite guidelines, the first line treatment for massive right colon cancer bleeding should ideally stop the bleeding using endoscopy or interventional radiology, subsequently allowing proper tumor staging and planning of a definite treatment strategy. Minimally invasive approaches for right and left colectomy have progressively increased and are widely performed in elective settings, with laparoscopy chosen in the majority of cases.

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Synopsis of recent research by authors named "Mara Disabato"

  • Mara Disabato's research primarily focuses on liver transplantation and surgical outcomes, particularly investigating alternative allocation methods for liver grafts and their impact on patient survival and graft quality.
  • In her studies, Disabato has examined "rescued" liver grafts that had been previously declined multiple times, finding insights on their effectiveness compared to standard MELD allocation procedures, thereby contributing valuable information to enhance decision-making in liver transplantation.
  • Additionally, Disabato has explored the complications in elderly patients undergoing digestive surgeries and evaluated the efficacy of robotic versus laparoscopic techniques in managing gastrointestinal tumors, aiming to improve clinical practices and patient outcomes in surgical oncology.